Magnetic Resonance Assessment of Left Ventricular Ejection Fraction at Any Time Post‐Infarction for Prediction of Subsequent Events in a Large Multicenter STEMI Registry

Background Magnetic resonance imaging (MRI) is the most accurate imaging technique for left ventricular ejection fraction (LVEF) quantification, but as yet the prognostic value of LVEF assessment at any time after ST‐segment elevation myocardial infarction (STEMI) for subsequent major adverse cardia...

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Published in:Journal of magnetic resonance imaging 2022-08, Vol.56 (2), p.476-487
Main Authors: Gavara, Jose, Marcos‐Garces, Victor, Lopez‐Lereu, Maria P., Monmeneu, Jose V., Rios‐Navarro, Cesar, Dios, Elena, Perez, Nerea, Merenciano, Hector, Gabaldon, Ana, Cànoves, Joaquim, Racugno, Paolo, Bonanad, Clara, Minana, Gema, Nunez, Julio, Nunez, Eduardo, Moratal, David, Chorro, Francisco J., Valente, Filipa, Lorenzatti, Daniel, Rodríguez‐Palomares, Jose F., Ortiz‐Pérez, Jose T., Bodi, Vicente
Format: Article
Language:English
Subjects:
Congestive heart failure
Ejection fraction
Field strength
Gadolinium
Imaging techniques
left ventricular ejection fraction
Magnetic resonance imaging
Markov chains
Medical imaging
Myocardial infarction
Population studies
Precession
prognosis
Resonance
risk
Statistical analysis
Statistical tests
ST‐segment elevation myocardial infarction
Ventricle
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Summary:Background Magnetic resonance imaging (MRI) is the most accurate imaging technique for left ventricular ejection fraction (LVEF) quantification, but as yet the prognostic value of LVEF assessment at any time after ST‐segment elevation myocardial infarction (STEMI) for subsequent major adverse cardiac event (MACE) prediction is uncertain. Purpose To explore the prognostic impact of MRI‐derived LVEF at any time post‐STEMI to predict subsequent MACE (cardiovascular death or re‐admission for acute heart failure). Study Type Prospective. Population One thousand thirteen STEMI patients were included in a multicenter registry. Field Strength/Sequence 1.5‐T. Balanced steady‐state free precession (cine imaging) and segmented inversion recovery steady‐state free precession (late gadolinium enhancement) sequences. Assessment Post‐infarction MRI‐derived LVEF (reduced [r]: 3 months of follow‐up. Statistical Tests Multi‐state Markov model to determine the prognostic value of each LVEF state (r‐, mr‐ or p‐) at any time point assessed to predict subsequent MACE. A P‐value
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.27789