The quantra hemostasis analyzer compared to thromboelastography (TEG) in the surgical oncologic population: A prospective observational trial

Background Management of coagulopathy during major oncologic surgery can be multifactorial and challenging. Viscoelastic assays (VEAs) can be useful in providing vital data about the mechanism of coagulopathy in these dynamic circumstances. Objectives A prospective nonrandomized observational study...

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Bibliographic Details
Published in:Journal of surgical oncology 2021-10, Vol.124 (5), p.894-905
Main Authors: Idowu, Olakunle, Ifeanyi‐Pillette, Ifey, Owusu‐Agyemang, Pascal, Holmes, Allen, Kwater, Piotr, Jackson, Timothy, Mena, Gabriel, Lasala, Javier, Heir, Jagtar Singh
Format: Article
Language:English
Subjects:
bleeding
cancer
Cancer surgery
Coagulation
coagulopathy
Hemorrhage
Observational studies
perioperative
point‐of‐care device
Surgical techniques
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Summary:Background Management of coagulopathy during major oncologic surgery can be multifactorial and challenging. Viscoelastic assays (VEAs) can be useful in providing vital data about the mechanism of coagulopathy in these dynamic circumstances. Objectives A prospective nonrandomized observational study with the aim of describing the coagulation parameters of patients undergoing major oncologic surgery using the Quantra® and TEG® 5000 systems. Our secondary objectives included the correlation between Quantra and TEG parameters, and the times to result for both technologies. Methods This study included 74 adults undergoing oncologic surgery with an anticipated blood loss of more than 500 ml. For each subject, whole blood samples for each device were collected at multiple points perioperatively for comparison. Results Correlation coefficients between Quantra and TEG parameters were 0.8 and above, indicating a very strong correlation (p 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.26578