Seroprevalence of Epstein-Barr virus and cytomegalovirus infections in Presidente Figueiredo, Amazonas, Brazil

Epstein-Barr virus (EBV) and cytomegalovirus (CMV) infections affect around 95% of the world's population. In Brazil, there are few epidemiological reports related to EBV and CMV infection, especially in the western Amazon region. This study aimed to estimate the seroprevalence of EBV and CMV i...

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Bibliographic Details
Published in:Journal of immunoassay & immunochemistry 2022-01, Vol.43 (1), p.67-77
Main Authors: de Castro Alves, Carlos Eduardo, Pinheiro-Silva, Renato, Silva, Marcus Tolentino, Galvão, Taís Freire, de Melo Silva, Jean, Moura Neto, José Pereira, Pontes, Gemilson Soares
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Antibodies
Brazil - epidemiology
Brazilian Amazon
Child
Child, Preschool
Children
coinfection
Cytomegalovirus
Cytomegalovirus Infections - epidemiology
Daycare
Enzyme-linked immunosorbent assay
Epidemiology
Epstein-Barr virus
Epstein-Barr Virus Infections - epidemiology
Herpesvirus 4, Human
herpevirus
Humans
Immunoglobulin G
Infections
Population studies
prevalence
Seroepidemiologic Studies
Serology
Viruses
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Summary:Epstein-Barr virus (EBV) and cytomegalovirus (CMV) infections affect around 95% of the world's population. In Brazil, there are few epidemiological reports related to EBV and CMV infection, especially in the western Amazon region. This study aimed to estimate the seroprevalence of EBV and CMV infection in individuals residents in Presidente Figueiredo, Amazonas, Brazil. Blood samples of 443 individuals were tested for the presence of anti-EBV and anti-CMV IgG antibodies through an enzyme-linked immunosorbent assay. EBV (95.9%; 95% CI: 0.94;0.98), CMV (96.8%; 95% CI: 0.95;0.98) and CMV/EBV (93%;95% CI: 0.91-0.95) coinfection were highly prevalent in the study population. Children (1 to 5 years) not attending school were less susceptible to EBV (OR 0.15; 95% CI: 0.05-0.52; p = 0.017) and CMV infections (OR 0.05; 95% CI: 0.02 − 0.17; p
ISSN:1532-1819
1532-4230
DOI:10.1080/15321819.2021.1942043