Nonhuman primate models for SARS-CoV-2 Research: Managing demand for specific-pathogen-free (SPF) animals

The SARS-CoV-2/COVID-19 pandemic has significantly increased the demand for specific-pathogen-free (SPF) nonhuman primates (NHPs) for development of vaccines and therapeutics, thus straining the supply of these animals for biomedical research studies. Non-SPF animals, which are available in greater...

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Bibliographic Details
Published in:Lab animal 2021-08, Vol.50 (8), p.200-201
Main Authors: Contreras, Miguel A., Arnegard, Matthew E., Chang, Michael C., Hild, Sheri, Grieder, Franziska, Murphy, Stephanie J.
Format: Article
Language:English
Subjects:
631/208/1348
692/308/1426
692/308/2778
Analysis
Animal experimentation
Animal Models
Animal models in research
Animals
Antiviral agents
Biomedical and Life Sciences
Comment
COVID-19
Disease Models, Animal
Evaluation
Humans
Life Sciences
Macaca mulatta
Pathogens
Primates
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Specific Pathogen-Free Organisms
Veterinary Medicine/Veterinary Science
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Summary:The SARS-CoV-2/COVID-19 pandemic has significantly increased the demand for specific-pathogen-free (SPF) nonhuman primates (NHPs) for development of vaccines and therapeutics, thus straining the supply of these animals for biomedical research studies. Non-SPF animals, which are available in greater numbers and include well-characterized primate species, should be considered in lieu of limited SPF animals for appropriate research studies.
ISSN:0093-7355
1548-4475
DOI:10.1038/s41684-021-00810-2