Is hip morphology a risk factor for developing hip osteoarthritis? A systematic review with meta-analysis

SummaryObjectiveTo appraise the highest evidence on hip morphology as a risk factor for developing hip osteoarthritis (OA). DesignWe searched for studies evaluating the association between radiological hip morphology parameters and the prevalence, incidence or progression of hip OA (based on differe...

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Bibliographic Details
Published in:Osteoarthritis and cartilage 2021-09, Vol.29 (9), p.1252-1264
Main Authors: Casartelli, N.C, Maffiuletti, N.A, Valenzuela, P.L, Grassi, A, Ferrari, E, van Buuren, M.M.A, Nevitt, M.C, Leunig, M, Agricola, R
Format: Article
Language:English
Subjects:
Cross-Sectional Studies
Disease Progression
Hip
Hip Joint - anatomy & histology
Hip Joint - diagnostic imaging
Humans
Imaging
Incidence
Meta-analysis
Morphology
Osteoarthritis
Osteoarthritis, Hip - epidemiology
Osteoarthritis, Hip - etiology
Prevalence
Prospective Studies
Radiography
Rheumatology
Risk Factors
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Summary:SummaryObjectiveTo appraise the highest evidence on hip morphology as a risk factor for developing hip osteoarthritis (OA). DesignWe searched for studies evaluating the association between radiological hip morphology parameters and the prevalence, incidence or progression of hip OA (based on different radiographic and clinical criteria) in the MEDLINE, EMBASE, Web of Science, Scopus, Cochrane Library and PEDro databases from inception until June 2020. Prospective and cross-sectional studies were separately evaluated. Data are presented as odds ratios (OR) with 95% confidence intervals (CI). ResultsWe included 9 prospective and 21 cross-sectional studies in the meta-analysis, and evaluated 42,831 hips from 25,898 individuals (mean age: 59 years). Prospective studies showed that, compared with control hips, hips with cam morphology (alpha angle >60°; OR = 2.52, 95% CI: 1.83 to 3.46, P 
ISSN:1063-4584
1522-9653
DOI:10.1016/j.joca.2021.06.007