Optimizing initial neonatal resuscitation to reduce neonatal encephalopathy around the world

One million two hundred thousand neonatal lives are lost each year due to intrapartum-related events; 99% of these deaths occur in low- and lower middle-income countries. Neonates exposed to intrapartum-related events present with failure to breathe at birth. Quick and effective delivery room manage...

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Bibliographic Details
Published in:Seminars in fetal & neonatal medicine 2021-08, Vol.26 (4), p.101262-101262, Article 101262
Main Authors: Patterson, Jackie, North, Krysten, Dempsey, Eugene, Ishoso, Daniel, Trevisanuto, Daniele, Lee, Anne CC, Kamath-Rayne, Beena D.
Format: Article
Language:English
Subjects:
Asphyxia neonatorum
Asphyxia Neonatorum - prevention & control
Bag-mask ventilation
Brain Diseases
Cardiopulmonary resuscitation
Extrauterine transition
Helping babies breathe
Humans
Infant Mortality
Infant, Newborn
Infant, Newborn, Diseases
Neonatal encephalopathy
Neonatal resuscitation
Neonatal transition
Resuscitation - education
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Summary:One million two hundred thousand neonatal lives are lost each year due to intrapartum-related events; 99% of these deaths occur in low- and lower middle-income countries. Neonates exposed to intrapartum-related events present with failure to breathe at birth. Quick and effective delivery room management of these neonates is critical in the prevention of brain injury. Given the prominent role of lung aeration in the cardiopulmonary transition at birth, the mainstay of neonatal resuscitation is effective ventilation. Basic neonatal resuscitation focuses on simple stimulation, airway positioning and clearing, and bag-mask ventilation. Although principles for basic neonatal resuscitation remain the same for high- and low-resource settings, guidelines may differ based on available human and material resources. Formal training in basic resuscitation reduces intrapartum-related neonatal mortality in low-resource settings. However, there remain opportunities to improve provider performance for increased impact with other strategies such as regular practice and continuous quality improvement.
ISSN:1744-165X
1878-0946
DOI:10.1016/j.siny.2021.101262