Lost in post-translational modification-Dengue virus writes its own sequel

Elevated frequency of afucosylated IgG1 antibodies during dengue virus infection is associated with prior infection and predicts severe disease. Elevated frequency of afucosylated IgG1 antibodies during dengue virus infection is associated with prior infection and predicts severe disease.

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Bibliographic Details
Published in:Science immunology 2021-07, Vol.6 (61)
Main Authors: Yandamuri, Soumya S, O'Connor, Kevin C
Format: Article
Language:English
Subjects:
Antibodies, Viral - blood
Antibodies, Viral - metabolism
Dengue Virus - immunology
Glycosylation
Humans
Immunoglobulin G - blood
Immunoglobulin G - metabolism
Protein Processing, Post-Translational - physiology
Severe Dengue - immunology
Severe Dengue - pathology
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Online Access:Get full text
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Description
Summary:Elevated frequency of afucosylated IgG1 antibodies during dengue virus infection is associated with prior infection and predicts severe disease. Elevated frequency of afucosylated IgG1 antibodies during dengue virus infection is associated with prior infection and predicts severe disease.
ISSN:2470-9468
2470-9468
DOI:10.1126/sciimmunol.abk1555