Efficacy and safety of surfactant administration via thin catheter in preterm infants with neonatal respiratory distress syndrome: A systematic review and meta‐analysis

Objective The efficacy and safety of surfactant administration via thin catheter in preterm infants with neonatal respiratory distress syndrome (NRDS) was investigated. Methods PubMed, Embase, Cochrane Library, and Web of Science databases were searched to identify randomized controlled trials (RCTs...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric pulmonology 2021-09, Vol.56 (9), p.3013-3025
Main Authors: Wu, Xiaohong, Feng, Zhoushan, Kong, Juan, Lai, Yiyu, Jia, Chunhong, Xu, Zhanyuan, Wu, Fan, Cui, Qiliang, Chen, Yaoyong
Format: Article
Language:English
Subjects:
bronchopulmonary dysplasia
Catheters
intubation‐surfactant‐extubation strategy
Meta-analysis
minimally invasive surfactant administration
neonatal respiratory distress syndrome
Newborn babies
Pneumothorax
Premature babies
Respiratory distress syndrome
Surfactants
Ventilators
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective The efficacy and safety of surfactant administration via thin catheter in preterm infants with neonatal respiratory distress syndrome (NRDS) was investigated. Methods PubMed, Embase, Cochrane Library, and Web of Science databases were searched to identify randomized controlled trials (RCTs) that comparing thin catheter technique with intubation for surfactant delivery in preterm infants with NRDS. Results Thirteen RCTs (1931 infants) were included in the meta‐analysis. The use of thin catheter technique decreased the incidences of bronchopulmonary dysplasia (BPD), pneumothorax, and hemodynamically significant patent ductus arteriosus (hsPDA) (risk ratio [RR]: 0.59, 95% confidence interval [CI]: 0.46–0.75, p 
ISSN:8755-6863
1099-0496
DOI:10.1002/ppul.25545