Prevalence and clinical characteristics of prediabetes and diabetes mellitus in young patients with ST-segment elevation myocardial infarction

Background Only few data on the prevalence of DM in young patients with ST-elevation myocardial infarction (STEMI) exist. Aim of the present study was to analyse this prevalence, its association to other cardiovascular risk factors and its impact on severity of CAD. In a substudy, consecutive HbA1c...

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Bibliographic Details
Published in:Clinical research in cardiology 2021-10, Vol.110 (10), p.1647-1658
Main Authors: Mata Marín, Luis Alberto, Schmucker, Johannes, Fach, Andreas, Osteresch, Rico, Rühle, Stephan, Garstka, Daniela, Eitel, Ingo, Hambrecht, Rainer, Wienbergen, Harm
Format: Article
Language:English
Subjects:
Adult
Blood Glucose - analysis
Cardiology
Cardiovascular diseases
Cohort Studies
Diabetes mellitus
Diabetes Mellitus - epidemiology
Female
Germany
Glycated Hemoglobin A - analysis
Health risks
Heart attacks
Heart Disease Risk Factors
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Myocardial infarction
Obesity
Original Paper
Patients
Percutaneous Coronary Intervention - methods
Prediabetic State - epidemiology
Prevalence
Registries
Risk analysis
Risk factors
Severity of Illness Index
ST Elevation Myocardial Infarction - therapy
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Summary:Background Only few data on the prevalence of DM in young patients with ST-elevation myocardial infarction (STEMI) exist. Aim of the present study was to analyse this prevalence, its association to other cardiovascular risk factors and its impact on severity of CAD. In a substudy, consecutive HbA1c measurements in each patient were evaluated. Methods All patients ≤ 45 years old, admitted with STEMI to an overregional German Heart Centre and treated with primary coronary intervention between 2006 and 2019, entered analysis. Since 2015 HbA1c measurements were performed to detect unknown dysglycaemia. Results Out of 776 young patients of the total cohort, 88 patients (11.4%) had a DM, while 688 (88.6%) did not. Diabetics were more likely to be obese (BMI ≥ 30 kg/m 2 , OR 2.4, 95%CI 1.4–4.0, p  
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-021-01868-1