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How different time intervals between repeated applications of CPP-ACP fluoride varnish effect smooth surface enamel demineralization?

To evaluate the preventive effects of different time intervals between repeated applications of the CPP-ACP fluoride varnish on enamel demineralization. Human teeth were sectioned and randomly allocated to three groups: 4-week, 6-week, and 12-week (N = 22/group). Baseline images of the enamel surfac...

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Published in:Journal of dentistry 2021-09, Vol.112, p.103742-103742, Article 103742
Main Authors: Abufarwa, Moufida, Noureldin, Amal, Campbell, Phillip M., Buschang, Peter H.
Format: Article
Language:English
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Summary:To evaluate the preventive effects of different time intervals between repeated applications of the CPP-ACP fluoride varnish on enamel demineralization. Human teeth were sectioned and randomly allocated to three groups: 4-week, 6-week, and 12-week (N = 22/group). Baseline images of the enamel surfaces were obtained using the FluoreCam recording the area, intensity, and impact of baseline enamel demineralization. All groups received fluoride varnish applications at the beginning of the experiment. The varnish was reapplied every 4 or 6 weeks in the 4-week and 6-week groups, respectively. Following each application, the groups underwent thermo-cycling, tooth brushing and pH cycling to simulate the time effect. After 12 weeks, the enamel surfaces were reimaged using the FluoreCam. Within and between-group differences in the area, intensity and impact of demineralization were evaluated. At baseline, there were no significant between-group differences for area, intensity, or impact. Statistically significant (p
ISSN:0300-5712
1879-176X
DOI:10.1016/j.jdent.2021.103742