Neobladder and ablative pelvic radiotherapy: still a taboo?

The presence of a neobladder constitutes a limitation for the radiation oncologist, as there is no clear evidence about its tolerance to radiotherapy (RT). The limited literature only concerns the conventional postoperative treatment in patients with bladder cancer after cystectomy. Here we report a...

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Bibliographic Details
Published in:Tumori 2021-12, Vol.107 (6), p.NP108-NP113
Main Authors: Bergamaschi, Luca, Gerardi, Marianna Alessandra, Zaffaroni, Mattia, Augugliaro, Matteo, Vigorito, Sabrina, Rondi, Elena, Della Vigna, Paolo, Varano, Gianluca, Fumagalli Romario, Uberto, Biffi, Roberto, Picardi, Edgardo Enrico Edoardo, Ferrari, Annamaria, Jereczek-Fossa, Barbara Alicja
Format: Article
Language:English
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Summary:The presence of a neobladder constitutes a limitation for the radiation oncologist, as there is no clear evidence about its tolerance to radiotherapy (RT). The limited literature only concerns the conventional postoperative treatment in patients with bladder cancer after cystectomy. Here we report a case of a patient with neobladder who underwent a stereotactic RT for a pelvic recurrence of disease, with response to treatment and no toxicity to the neobladder. This case represents a promising example of the chance to perform RT with ablative intent, using advanced techniques, even on lesions close to the neobladder.
ISSN:0300-8916
2038-2529
DOI:10.1177/03008916211031295