Seroprevalence of Strongyloides stercoralis among patients with leptospirosis in northern Iran: a descriptive cross-sectional study

Strongyloidiasis and leptospirosis are neglected tropical diseases that have affected many countries across the world. In this study, we evaluated the seroprevalence of Strongyloides stercoralis among patients with leptospirosis in northern Iran. We evaluated 156 laboratory- or clinically confirmed...

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Bibliographic Details
Published in:Journal of helminthology 2021, Vol.95, p.e34-e34, Article e34
Main Authors: Varzegar, P., Bayani, M., Kalantari, N., Nasiri-kenari, M., Amini Navaie, B., Mollalo, A., Rostami, A.
Format: Article
Language:English
Subjects:
Alanine
Alanine transaminase
Aspartate aminotransferase
Confidence intervals
Creatinine
Cross-sectional studies
Evaluation
Gastrointestinal diseases
Laboratories
Larvae
Leptospirosis
Medical research
Parasites
Parasitic diseases
Patients
Public health
Risk analysis
Risk factors
Serology
Short Communication
Strongyloides stercoralis
Strongyloidiasis
Transaminases
Tropical climate
Tropical diseases
Worms
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Summary:Strongyloidiasis and leptospirosis are neglected tropical diseases that have affected many countries across the world. In this study, we evaluated the seroprevalence of Strongyloides stercoralis among patients with leptospirosis in northern Iran. We evaluated 156 laboratory- or clinically confirmed leptospirosis cases. The overall seroprevalence of S. stercoralis was 32.0% (95% confidence interval (CI): 27.4–36.5%, 50/156). Seropositivity was significantly associated with agricultural activities (odds ratio (OR): 2.84, 95% CI: 1.0–8.77) and gastrointestinal disorders (OR: 2.4, 95% CI: 1.1–4.9). Laboratory findings indicated that seropositivity of S. stercoralis was significantly associated with decreased levels of platelet and elevated levels of creatinine, alanine aminotransferase and aspartate aminotransferase (P < 0.05). Our findings suggested a higher exposure to S. stercoralis larvae among patients with leptospirosis. The public health and medical communities may benefit from this research through preventive measures to improve farmers’ knowledge and awareness regarding strongyloidiasis and leptospirosis and the associated risk factors.
ISSN:0022-149X
1475-2697
DOI:10.1017/S0022149X21000237