Recent progress in the optical detection of pathogenic bacteria based on noble metal nanoparticles

Pathogenic bacteria have become a huge threat to social health and economy for their frighteningly infectious and lethal capacity. It is quite important to make a diagnosis in advance to prevent infection or allow a rapid treatment after infection. Noble metal nanoparticles, due to their unique phys...

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Bibliographic Details
Published in:Mikrochimica acta (1966) 2021-08, Vol.188 (8), p.258-258, Article 258
Main Authors: Yang, Shou-Zhi, Liu, Qi-Ao, Liu, Yan-Ling, Weng, Guo-Jun, Zhu, Jian, Li, Jian-Jun
Format: Article
Language:English
Subjects:
Algorithms
Analytical Chemistry
Bacteria
Bacteria - isolation & purification
Bacteriological Techniques - instrumentation
Bacteriological Techniques - methods
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Chemistry Techniques, Analytical - instrumentation
Chemistry Techniques, Analytical - methods
Diagnosis
Gold
Health aspects
Infection
Metal Nanoparticles - chemistry
Metals, Heavy - chemistry
Microengineering
Nanochemistry
Nanoparticles
Nanotechnology
Noble metals
Optical properties
Point-of-Care Testing
Review Article
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Summary:Pathogenic bacteria have become a huge threat to social health and economy for their frighteningly infectious and lethal capacity. It is quite important to make a diagnosis in advance to prevent infection or allow a rapid treatment after infection. Noble metal nanoparticles, due to their unique physicochemical properties, especially optical properties, have drawn a great attention during the past decades and have been widely applied into all kinds of fields related to human health. By utilizing these noble metal nanoparticles, optical diagnosis platforms towards pathogenic bacteria have emerged continually, providing highly sensitive, selective, and particularly facile detection tools for clinic or point-of-care diagnosis. This review summarizes the recent development in this field. It begins with a brief introduction of pathogenic bacteria and noble metal nanoparticles. And then, optical detection methods are systematically discussed in three distinct aspects. In addition to these proof-of-concept methods, corresponding algorithms and point-of-care detection devices are also described. Finally, the review ends up with subjective views on present limitations and some appropriate advice for future research directions. Graphical abstract
ISSN:0026-3672
1436-5073
DOI:10.1007/s00604-021-04885-z