α‑Alkylation of Ketones with Alkenes Enabled by Photoinduced Activation of Silyl Enol Ethers in the Presence of a Small Amount of Water

Under blue-light irradiation conditions with a photocatalyst [1,2,3,5-tetrakis­(carbazol-9-yl)-4,6-dicyanobenzene], silyl enol ethers reacted with alkenes in the presence of a small amount of water to afford the α-alkylation products in good to high yields. A thiol cocatalyst was found to expand the...

Full description

Saved in:
Bibliographic Details
Published in:Organic letters 2021-08, Vol.23 (15), p.5693-5697
Main Authors: Hirata, Tsubasa, Ogasawara, Yoshihiro, Yamashita, Yasuhiro, Kobayashi, Shu̅
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Under blue-light irradiation conditions with a photocatalyst [1,2,3,5-tetrakis­(carbazol-9-yl)-4,6-dicyanobenzene], silyl enol ethers reacted with alkenes in the presence of a small amount of water to afford the α-alkylation products in good to high yields. A thiol cocatalyst was found to expand the substrate scope of the reaction.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.1c01824