Volume control: Turning the dial on regulatory T cells

Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function. Treg-mediated imm...

Full description

Saved in:
Bibliographic Details
Published in:Cell 2021-07, Vol.184 (15), p.3847-3849
Main Authors: Brown, Chrysothemis C., Gottschalk, Rachel A.
Format: Article
Language:English
Subjects:
Immune Tolerance
Immunosuppression Therapy
T-Lymphocytes, Regulatory - immunology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c400t-79e5d87428a559846fb59fd9594ca8019973dcbcbc12eb47ab202ead17dac6743
cites cdi_FETCH-LOGICAL-c400t-79e5d87428a559846fb59fd9594ca8019973dcbcbc12eb47ab202ead17dac6743
container_end_page 3849
container_issue 15
container_start_page 3847
container_title Cell
container_volume 184
creator Brown, Chrysothemis C.
Gottschalk, Rachel A.
description Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function. Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function.
doi_str_mv 10.1016/j.cell.2021.06.015
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2555108869</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0092867421007509</els_id><sourcerecordid>2555108869</sourcerecordid><originalsourceid>FETCH-LOGICAL-c400t-79e5d87428a559846fb59fd9594ca8019973dcbcbc12eb47ab202ead17dac6743</originalsourceid><addsrcrecordid>eNp9kE1OwzAQhS0EglK4AAuUJZuEsRvHNmKDKv4kJDaFreXY05IqjcFOkLgNZ-FkOCqwRLOYzffezHuEnFAoKNDqfF1YbNuCAaMFVAVQvkMmFJTISyrYLpkAKJbLSpQH5DDGNQBIzvk-OZiVTAnF5ISIZ98OG8ys7_rg24tsMYSu6VZZ_4KZa0yb-S4LuBpa0_vwkS2-Psej8YjsLU0b8fhnT8nTzfVifpc_PN7ez68eclsC9LlQyJ0UJZOGcyXLallztXSKq9IaCVQpMXO2TkMZ1qUwdUqDxlHhjE2Pz6bkbOv7GvzbgLHXmyaOH5gO_RA1S4EoSFmphLItaoOPMeBSv4ZmY8KHpqDHwvRaj0o9Fqah0qmwJDr98R_qDbo_yW9DCbjcAphSvjcYdLQNdhZdE9D22vnmP_9vmt98IQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2555108869</pqid></control><display><type>article</type><title>Volume control: Turning the dial on regulatory T cells</title><source>ScienceDirect (Online service)</source><creator>Brown, Chrysothemis C. ; Gottschalk, Rachel A.</creator><creatorcontrib>Brown, Chrysothemis C. ; Gottschalk, Rachel A.</creatorcontrib><description>Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function. Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function.</description><identifier>ISSN: 0092-8674</identifier><identifier>EISSN: 1097-4172</identifier><identifier>DOI: 10.1016/j.cell.2021.06.015</identifier><identifier>PMID: 34297928</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Immune Tolerance ; Immunosuppression Therapy ; T-Lymphocytes, Regulatory - immunology</subject><ispartof>Cell, 2021-07, Vol.184 (15), p.3847-3849</ispartof><rights>2021 Elsevier Inc.</rights><rights>Copyright © 2021 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-79e5d87428a559846fb59fd9594ca8019973dcbcbc12eb47ab202ead17dac6743</citedby><cites>FETCH-LOGICAL-c400t-79e5d87428a559846fb59fd9594ca8019973dcbcbc12eb47ab202ead17dac6743</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0092867421007509$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3549,27924,27925,45780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34297928$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brown, Chrysothemis C.</creatorcontrib><creatorcontrib>Gottschalk, Rachel A.</creatorcontrib><title>Volume control: Turning the dial on regulatory T cells</title><title>Cell</title><addtitle>Cell</addtitle><description>Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function. Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function.</description><subject>Immune Tolerance</subject><subject>Immunosuppression Therapy</subject><subject>T-Lymphocytes, Regulatory - immunology</subject><issn>0092-8674</issn><issn>1097-4172</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kE1OwzAQhS0EglK4AAuUJZuEsRvHNmKDKv4kJDaFreXY05IqjcFOkLgNZ-FkOCqwRLOYzffezHuEnFAoKNDqfF1YbNuCAaMFVAVQvkMmFJTISyrYLpkAKJbLSpQH5DDGNQBIzvk-OZiVTAnF5ISIZ98OG8ys7_rg24tsMYSu6VZZ_4KZa0yb-S4LuBpa0_vwkS2-Psej8YjsLU0b8fhnT8nTzfVifpc_PN7ez68eclsC9LlQyJ0UJZOGcyXLallztXSKq9IaCVQpMXO2TkMZ1qUwdUqDxlHhjE2Pz6bkbOv7GvzbgLHXmyaOH5gO_RA1S4EoSFmphLItaoOPMeBSv4ZmY8KHpqDHwvRaj0o9Fqah0qmwJDr98R_qDbo_yW9DCbjcAphSvjcYdLQNdhZdE9D22vnmP_9vmt98IQ</recordid><startdate>20210722</startdate><enddate>20210722</enddate><creator>Brown, Chrysothemis C.</creator><creator>Gottschalk, Rachel A.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20210722</creationdate><title>Volume control: Turning the dial on regulatory T cells</title><author>Brown, Chrysothemis C. ; Gottschalk, Rachel A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-79e5d87428a559846fb59fd9594ca8019973dcbcbc12eb47ab202ead17dac6743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Immune Tolerance</topic><topic>Immunosuppression Therapy</topic><topic>T-Lymphocytes, Regulatory - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brown, Chrysothemis C.</creatorcontrib><creatorcontrib>Gottschalk, Rachel A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cell</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brown, Chrysothemis C.</au><au>Gottschalk, Rachel A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Volume control: Turning the dial on regulatory T cells</atitle><jtitle>Cell</jtitle><addtitle>Cell</addtitle><date>2021-07-22</date><risdate>2021</risdate><volume>184</volume><issue>15</issue><spage>3847</spage><epage>3849</epage><pages>3847-3849</pages><issn>0092-8674</issn><eissn>1097-4172</eissn><abstract>Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function. Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>34297928</pmid><doi>10.1016/j.cell.2021.06.015</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0092-8674
ispartof Cell, 2021-07, Vol.184 (15), p.3847-3849
issn 0092-8674
1097-4172
language eng
recordid cdi_proquest_miscellaneous_2555108869
source ScienceDirect (Online service)
subjects Immune Tolerance
Immunosuppression Therapy
T-Lymphocytes, Regulatory - immunology
title Volume control: Turning the dial on regulatory T cells
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T06%3A56%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Volume%20control:%20Turning%20the%20dial%20on%20regulatory%20T%C2%A0cells&rft.jtitle=Cell&rft.au=Brown,%20Chrysothemis%20C.&rft.date=2021-07-22&rft.volume=184&rft.issue=15&rft.spage=3847&rft.epage=3849&rft.pages=3847-3849&rft.issn=0092-8674&rft.eissn=1097-4172&rft_id=info:doi/10.1016/j.cell.2021.06.015&rft_dat=%3Cproquest_cross%3E2555108869%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c400t-79e5d87428a559846fb59fd9594ca8019973dcbcbc12eb47ab202ead17dac6743%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2555108869&rft_id=info:pmid/34297928&rfr_iscdi=true