Neurotrophic Effect of Magnesium Comenate in Normal and under Conditions of Oxidative Stress in Culture of Chicken Spinal Ganglia

The neurotrophic properties of magnesium comenate were studied under standard conditions and under conditions of oxidative stress. It was found that magnesium comenate has a stimulating effect on the neurotrophic processes of the spinal ganglia under normal conditions and under conditions of oxidati...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2021-07, Vol.171 (3), p.338-341
Main Authors: Shurygina, L. V., Zlishcheva, E. I., Kravtsov, A. A., Kozin, S. V.
Format: Article
Language:English
Subjects:
Amino acids
Animals
Antioxidants
Biomedical and Life Sciences
Biomedicine
Carboxylic Acids - pharmacology
Cell Biology
Chick Embryo
Dorsal root ganglia
Ganglia, Spinal - drug effects
Ganglia, Spinal - metabolism
Hydrogen Peroxide - antagonists & inhibitors
Hydrogen Peroxide - pharmacology
Internal Medicine
Laboratory Medicine
Magnesium
Magnesium Compounds - pharmacology
Neuronal Outgrowth - drug effects
Neurons
Neuroprotective Agents - pharmacology
Oxidation
Oxidative Stress
Pathology
Pyrones - pharmacology
Supply and demand
Tissue Culture Techniques
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Summary:The neurotrophic properties of magnesium comenate were studied under standard conditions and under conditions of oxidative stress. It was found that magnesium comenate has a stimulating effect on the neurotrophic processes of the spinal ganglia under normal conditions and under conditions of oxidative stress. Under standard conditions, magnesium comenate exhibits neurotrophic activity at a concentration of 0.0001 mM, under conditions of oxidative stress, magnesium comenate exhibits neurotrophic activity at concentration 0.1 mM.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-021-05223-2