The role of NBI with flexible video-endoscope in the follow-up of head and neck cancer patients: a prospective study

Purpose Narrow band imaging (NBI) enhances mucosal vasculature and could help in the identification of recurrences. We assessed the effectiveness of NBI with flexible video-endoscope in the early detection of recurrence after treatment of head and neck squamous cell carcinoma, its diagnostic advanta...

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Bibliographic Details
Published in:European archives of oto-rhino-laryngology 2022-04, Vol.279 (4), p.2133-2141
Main Authors: Boscolo Nata, Francesca, Gardenal, Nicoletta, Giudici, Fabiola, Tirelli, Giancarlo
Format: Article
Language:English
Subjects:
Head and Neck
Head and Neck Surgery
Medicine
Medicine & Public Health
Neurosurgery
Otorhinolaryngology
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Summary:Purpose Narrow band imaging (NBI) enhances mucosal vasculature and could help in the identification of recurrences. We assessed the effectiveness of NBI with flexible video-endoscope in the early detection of recurrence after treatment of head and neck squamous cell carcinoma, its diagnostic advantage over high-definition white-light (HD WL) endoscopy, also in relation to recurrence site, and the influence of previous radiotherapy (RT) or chemotherapy (CT). Moreover, we investigated the association between index tumor site and the risk of developing recurrence, and the relation between index tumor site and recurrence site. Methods From January 2018 to November 2020, 160 patients previously treated with surgery and/or RT ± CT were evaluated using NBI with flexible video-endoscope. Sensitivity, specificity, positive/negative predictive value, and accuracy were calculated for NBI and HD WL, and compared using the McNemar test. The Fisher exact test was used to compare the other associations investigated. Results The difference between NBI and HD WL sensitivity was statistically significant ( p  
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-021-07016-9