Long noncoding RNAs as biomarkers for the diagnosis of hepatocellular carcinoma: A meta-analysis

Long non-coding RNAs (lncRNAs) are often aberrantly expressed in hepatocellular carcinoma (HCC). The role of lncRNAs in the diagnosis of HCC has attracted increasing attention. Hence, we performed a meta-analysis based on current studies to assess the diagnostic value of lncRNAs for HCC. A systemati...

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Bibliographic Details
Published in:Pathology, research and practice research and practice, 2021-08, Vol.224, p.153546-153546, Article 153546
Main Authors: Zeng, Chuyi, Tang, Yan, Jiang, Yao, Zuo, Zhihua, Tao, Hualin
Format: Article
Language:English
Subjects:
Area Under Curve
Biomarkers, Tumor - genetics
Carcinoma, Hepatocellular - diagnosis
Carcinoma, Hepatocellular - genetics
Diagnosis
Hepatocellular carcinoma
Humans
Liver Neoplasms - diagnosis
Liver Neoplasms - genetics
LncRNAs
Meta-analysis
RNA, Long Noncoding - genetics
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Summary:Long non-coding RNAs (lncRNAs) are often aberrantly expressed in hepatocellular carcinoma (HCC). The role of lncRNAs in the diagnosis of HCC has attracted increasing attention. Hence, we performed a meta-analysis based on current studies to assess the diagnostic value of lncRNAs for HCC. A systematic search was performed using PubMed, Web of Science, and Embase databases for relevant studies. The quality of the studies was assessed with the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2). A fixed-effect model was used if the value of I2 statistics
ISSN:0344-0338
1618-0631
DOI:10.1016/j.prp.2021.153546