Direct admission vs. secondary transfer for mechanical thrombectomy: long-term clinical outcomes from a single Polish Comprehensive Stroke Centre

We aimed to compare 3-month clinical outcomes after mechanical thrombectomy (MT) in patients transferred directly to a comprehensive stroke centre ('mothership', MS) to the outcomes of patients transferred secondarily from primary stroke centres ('drip-and-ship', DAS) in Lubelski...

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Bibliographic Details
Published in:Neurologia i neurochirurgia polska 2021, Vol.55 (5), p.494-498
Main Authors: Luchowski, Piotr, Wojczal, Joanna, Prus, Katarzyna, Szmygin, Maciej, Sojka, Michał, Luchowska, Elżbieta, Rejdak, Konrad
Format: Article
Language:English
Subjects:
Brain Ischemia - surgery
Clinical outcomes
Hemorrhage
Hospitalization
Humans
Ischemia
Laboratories
Medical imaging
Mortality
Patient Transfer
Poland
Prospective Studies
Retrospective Studies
Statistical analysis
Stroke
Stroke - surgery
Thrombectomy
Treatment Outcome
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Summary:We aimed to compare 3-month clinical outcomes after mechanical thrombectomy (MT) in patients transferred directly to a comprehensive stroke centre ('mothership', MS) to the outcomes of patients transferred secondarily from primary stroke centres ('drip-and-ship', DAS) in Lubelskie province, the third largest province in Poland. In a prospective stroke registry, all patients with large vessel occlusion in anterior circulation admitted within six hours of onset and treated with MT between 2017 and 2020 were retrospectively analysed. A total of 400 patients was evaluated: 267 treated with the MS approach and 133 with the DAS approach. Time from stroke onset to groin puncture was shorter in the MS group. There was a significant difference in 3-month excellent clinical outcomes (mRS 0-1) between these two groups (32.9% of MS patients vs. 22.5% of DAS patients, p < 0.05), but there was no difference if the 3-month endpoint was expressed as mRS ≤ 2 (42.3% of MS vs. 34.5% of DAS patients, p = 0.13). The rate of symptomatic intracranial haemorrhage and mortality was comparable in both groups. Our study shows that direct admission to a comprehensive stroke centre resulted in more patients achieving excellent treatment outcomes (mRS 0-1). At the same time, the superiority of the MT model over the DAS model in obtaining mRS 0-2 was not unequivocally demonstrated. Further studies are needed to determine the best stroke model for patients potentially eligible for MT.
ISSN:0028-3843
1897-4260
DOI:10.5603/PJNNS.a2021.0050