Very-low-calorie ketogenic diet: An alternative to a pharmacological approach to improve glycometabolic and gonadal profile in men with obesity

Obesity and metabolic diseases have become a worrying reality, especially in more developed societies. They are associated with the development of many comorbidities, such as type 2 diabetes mellitus, hypogonadism, hypertension, cerebrovascular and cardiovascular diseases, neoplasia, obstructive sle...

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Bibliographic Details
Published in:Current opinion in pharmacology 2021-10, Vol.60, p.72-82
Main Authors: Mongioì, Laura M., Cimino, Laura, Greco, Emanuela, Cannarella, Rossella, Condorelli, Rosita A., La Vignera, Sandro, Calogero, Aldo E.
Format: Article
Language:English
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Summary:Obesity and metabolic diseases have become a worrying reality, especially in more developed societies. They are associated with the development of many comorbidities, such as type 2 diabetes mellitus, hypogonadism, hypertension, cerebrovascular and cardiovascular diseases, neoplasia, obstructive sleep apnea, and non-alcoholic fatty liver disease. Therefore, weight loss is of paramount importance. A promising therapeutic option to achieve this goal is the very-low-calorie ketogenic diet. This review aims to summarize the main effects of very-low-calorie–ketogenic diet on the glycometabolic and gonadal profiles of men with overweight/obesity.
ISSN:1471-4892
1471-4973
DOI:10.1016/j.coph.2021.06.013