Novel Fe3O4@metal-organic framework@polymer core-shell-shell nanospheres for fast extraction and specific preconcentration of nine organophosphorus pesticides from complex matrices

• Published in: Food chemistry 2021-12, Vol.365, p.130485-130485, Article 130485
• Main Authors: Wan, Mengfei, Xiang, Fachun, Liu, Zhongdong, Guan, Denggao, Shao, Yong, Zheng, Lufei, Jin, Maojun, She, Yongxin, Cao, Liping, Jin, Fen, Chen, Rui, Wang, Shanshan, Wu, Yijun, Abd El-Aty, A.M., Wang, Jing
• Format: Article
• Language: English
• Subjects: Analysis; Environmental water; Food samples; Magnetic solid-phase extraction; Metal-organic frameworks; Organophosphorus pesticides; Polymer
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2021.130485

[Display omitted] •A novel Fe3O4@ZIF-8@polymer core-shell-shell nanosphere was fabricated via a facile and versatile modification strategy.•Functional polymer modification substantially improved the extraction performance of Fe3O4@ZIF-8 for OPPs.•Magnetic core endowed fast separation and simplified the pre-treatment process.•A high sensitive and reliable MSPE-LC/MS-MS method was developed and validated.•It can be used for simultaneous monitoring of multiple OPPs in various matrices at trace levels. Herein, a novel core-shell-shell magnetic nanosphere denoted as Fe3O4@ZIF-8@polymer was fabricated by sequential in situ self-assembly and precipitation polymerization for effective magnetic solid-phase extraction of nine organophosphorus pesticides (OPPs) from river water, pear, and cabbage samples. The integrated Fe3O4@ZIF-8@polymer featured convenient magnetic separation property and excellent multi-target binding ability. More importantly, the functional polymer coating greatly improved the extraction performance of Fe3O4@ZIF-8 for OPPs, thus facilitating the simultaneous determination of trace OPP residues in real samples. The developed MPSE-LC-MS/MS method exhibited good linearity (R2 ≥ 0.9991) over the concentration range of 0.2–200 µg L−1, low limits of detection of 0.0002–0.005 μg L−1 for river water and 0.006–0.185 μg kg−1 for pear and cabbage, satisfactory precision with relative standard deviations ≤ 9.7% and accuracy with recoveries of 69.5–94.3%. These results highlight that the combination of polymers with MOFs has great potential to fabricate excellent adsorbents for high-throughput analysis of various contaminants in complex matrices.