Highly Sensitive Fluorescent pH Microsensors Based on the Ratiometric Dye Pyranine Immobilized on Silica Microparticles

Invited for the cover of this issue are Anil Chandra, Loretta L. del Mercato and co‐workers at the Institute of Nanotechnology of National Research Council and the University of Salento. The image depicts how negatively charged pH‐sensitive pyranine (HPTS) molecules were successfully immobilized on...

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Published in:Chemistry : a European journal 2021-09, Vol.27 (53), p.13279-13279
Main Authors: Chandra, Anil, Prasad, Saumya, Iuele, Helena, Colella, Francesco, Rizzo, Riccardo, D'Amone, Eliana, Gigli, Giuseppe, Mercato, Loretta L.
Format: Article
Language:English
Subjects:
Biocompatibility
Chemistry
Fluorescence
Microparticles
Nanotechnology
pH effects
Silica
Silicon dioxide
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container_end_page 13279
container_issue 53
container_start_page 13279
container_title Chemistry : a European journal
container_volume 27
creator Chandra, Anil
Prasad, Saumya
Iuele, Helena
Colella, Francesco
Rizzo, Riccardo
D'Amone, Eliana
Gigli, Giuseppe
Mercato, Loretta L.
description Invited for the cover of this issue are Anil Chandra, Loretta L. del Mercato and co‐workers at the Institute of Nanotechnology of National Research Council and the University of Salento. The image depicts how negatively charged pH‐sensitive pyranine (HPTS) molecules were successfully immobilized on silica microparticles (SMPs) without compromising the molecules′ pH sensitivity. These resulting sensors can be used to measure pH in vitro and in vivo due to the cytocompatibility of HPTS molecules and SMPs. Read the full text of the article at 10.1002/chem.202101568. “In this work, we successfully embedded HPTS molecules in silica microparticles but still retained their pH sensitivity. The synthesized pH‐sensitive microparticles were stable and showed a remarkable sensitivity to pH change.” Read more about the story behind the cover in the Cover Profile and about the research itself on page 13318 ff. (DOI: 10.1002/chem.202101568).
doi_str_mv 10.1002/chem.202102674
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subjects Biocompatibility
Chemistry
Fluorescence
Microparticles
Nanotechnology
pH effects
Silica
Silicon dioxide
title Highly Sensitive Fluorescent pH Microsensors Based on the Ratiometric Dye Pyranine Immobilized on Silica Microparticles
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