Decision-making in active surveillance in kidney cancer: current trends and future urine and tissue markers

Surveillance for small renal masses is a growing choice of management amongst physicians and patients. These decisions, however, can be difficult as patient factors and tumor factors may blur the line between continued surveillance and intervention. Currently, there are no biomarkers that are readil...

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Bibliographic Details
Published in:World journal of urology 2021-08, Vol.39 (8), p.2869-2874
Main Authors: Patel, Sunil H., Singla, Nirmish, Pierorazio, Phillip M.
Format: Article
Language:English
Subjects:
Biomarkers
Biomarkers, Tumor - analysis
Carcinoma, Renal Cell - metabolism
Carcinoma, Renal Cell - pathology
Carcinoma, Renal Cell - therapy
Clinical Decision-Making
Decision making
Humans
Kidney cancer
Kidney Neoplasms - metabolism
Kidney Neoplasms - pathology
Kidney Neoplasms - therapy
Medicine
Medicine & Public Health
Nephrology
Oncology
Renal cell carcinoma
Surveillance
Topic Paper
Urology
Watchful Waiting - methods
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Summary:Surveillance for small renal masses is a growing choice of management amongst physicians and patients. These decisions, however, can be difficult as patient factors and tumor factors may blur the line between continued surveillance and intervention. Currently, there are no biomarkers that are readily available to aid in the decision making for patients with known renal cell carcinoma; however, many show promise. We herein review the literature of the adjunct tools that are currently available for decision making in small renal masses, but also new potential biomarkers that can potentially be of use.
ISSN:0724-4983
1433-8726
DOI:10.1007/s00345-021-03786-3