Koninginin W, a New Polyketide from the Endophytic Fungus Trichoderma koningiopsis YIM PH30002

A new compound named koninginin W (1) and four known polyketides (2–5) were isolated from endophytic fungus Trichoderma koningiopsis YIM PH30002 of Panax notoginseng. The structures of 1 ‐ 5, including absolute configuration of 1, were elucidated on the detailed analysis of the HR‐ESI‐MS, 1D and 2D...

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Bibliographic Details
Published in:Chemistry & biodiversity 2021-09, Vol.18 (9), p.e2100460-n/a
Main Authors: Wang, Yong‐Liang, Hu, Bin‐Yuan, Qian, Meng‐An, Wang, Zi‐Hang, Zou, Jing‐Mei, Sang, Xu‐Yan, Li, Lei, Luo, Xiao‐Dong, Zhao, Li‐Xing
Format: Article
Language:English
Subjects:
Absolute configuration
Antibacterial activity
Crystallography
E coli
Endophytes
Fungi
NMR
Nuclear magnetic resonance
polyketide
Polyketides
Salmonella
Trichoderma
Trichoderma koningiopsis
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Summary:A new compound named koninginin W (1) and four known polyketides (2–5) were isolated from endophytic fungus Trichoderma koningiopsis YIM PH30002 of Panax notoginseng. The structures of 1 ‐ 5, including absolute configuration of 1, were elucidated on the detailed analysis of the HR‐ESI‐MS, 1D and 2D NMR, and X‐ray crystallographic data. Koninginin W (1) presented weak antibacterial activity against Escherichia coli, Bacillus subtilis and Salmonella typhimurium.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.202100460