Magnetic layered double hydroxide/zeolitic imidazolate framework-8 nanocomposite as a novel adsorbent for enrichment of four endocrine disrupting compounds in milk samples

• Published in: Journal of hazardous materials 2022-01, Vol.421, p.126753-126753, Article 126753
• Main Authors: Di, Xin, Wang, Hanyang, Guo, Xiaoli, Wang, Xin, Liu, Youping
• Format: Article
• Language: English
• Subjects: Dispersive micro-solid phase extraction; Endocrine disrupting compounds; Layered double hydroxides; Nanocomposite; UHPLC-MS/MS; Zeolitic imidazolate frameworks
• ISSN: 0304-3894; 1873-3336
• DOI: 10.1016/j.jhazmat.2021.126753

For the first time, a novel nanocomposite, zeolitic imidazolate framework/magnetic layered double hydroxide (Fe3O4@LDH/ZIF), was successfully fabricated through in situ synthetic method with Fe3O4 as magnetic core and composite as shell. The resulting materials were characterized by XRD, TEM, FT-IR, VSM, TGA and nitrogen adsorption-desorption analysis. The Fe3O4@LDH/ZIF was employed as a sorbent in dispersive micro-solid phase extraction (D-μ-SPE) for enrichment of four endocrine disrupting compounds (EDCs) from milk samples prior to ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) analysis. The synthesized nanocomposite showed bigger specific surface area and better absorption capacity than Fe3O4@LDH. The equilibrium adsorption capacities (Qe, mg/g) of EDCs on the Fe3O4@LDH/ZIF reached up to 47.4–138.8 mg/g, mainly resulting from hydrogen bonding, π-π interaction and electrostatic interaction between EDCs and nanocomposite. Several variables affecting the extraction efficiency were investigated and optimized. The method displays low limits of detection (3–15 ng L−1), good linearity (10–5000 ng L−1), acceptable precision (RSD