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Comparison of MRI appendix biometrics in children with and without acute appendicitis

Objectives The goal of this study is to improve MRI-specific diagnostic criteria for pediatric appendicitis through comparison of normal and abnormal appendix–related imaging features. Methods A retrospective multireader-multicase design was used, including non-contrast MRI performed for suspected p...

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Bibliographic Details
Published in:European radiology 2022-02, Vol.32 (2), p.1024-1033
Main Authors: Tung, Eric L., Baird, Grayson L., Ayyala, Rama S., Sams, Cassandra, Herliczek, Thaddeus W., Swenson, David W.
Format: Article
Language:English
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Summary:Objectives The goal of this study is to improve MRI-specific diagnostic criteria for pediatric appendicitis through comparison of normal and abnormal appendix–related imaging features. Methods A retrospective multireader-multicase design was used, including non-contrast MRI performed for suspected pediatric appendicitis following non-diagnostic US from January 2014 to December 2017. Positive diagnosis was defined by surgical pathology or symptom resolution after antibiotics. Four pediatric radiologists independently graded study biometrics while blinded to clinical data. Balanced complete block design was used to determine performance characteristics. Results Global diagnosis of appendicitis (208 studies) had sensitivity 90.6% and specificity 97.7%. Median appendix diameter was 10.4 mm among positive cases and 5.8 mm among negative cases ( p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-021-08120-4