The importance of first trimester screening of cranial posterior fossa in predicting posterior fossa malformations which may be identified in the following weeks of gestation

Purpose We aimed to investigate the value of posterior fossa ultrasonography measurements in predicting fetal posterior fossa anomaly at 11–14 weeks of gestation. Methods The study was performed at Zeynep Kamil Women and Children's Diseases Training and Research Hospital. Measurements were made...

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Bibliographic Details
Published in:Journal of clinical ultrasound 2021-11, Vol.49 (9), p.958-962
Main Authors: Eric Ozdemir, Mucize, Demirci, Oya, Ayvaci Tasan, Habibe, Ohanoglu, Karolin, Akalin, Munip
Format: Article
Language:English
Subjects:
Abnormalities
Anomalies
Brain stem
brainstem
brainstem‐to‐occipital bone
fetus
Fetuses
Gestation
intracranial translucency
Occipital bone
Statistical analysis
Ultrasonic imaging
ultrasonography
Ventricle
Ventricles (cerebral)
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Summary:Purpose We aimed to investigate the value of posterior fossa ultrasonography measurements in predicting fetal posterior fossa anomaly at 11–14 weeks of gestation. Methods The study was performed at Zeynep Kamil Women and Children's Diseases Training and Research Hospital. Measurements were made in two groups: the control group consisted of 328 fetuses with normal postnatal outcome and the study group consisted of 22 fetuses with enlarged 4th ventricle. In the study group, we questioned the value of intracranial translucency (IT) and brainstem (BS) measurements and the BS/brainstem‐to‐occipital bone (BSOB) ratio in order to predict possible posterior fossa anomalies that may be identified in advanced gestational weeks. The differences of ultrasonographic measurements between groups with p  0.05). Conclusion IT, BSOB, and BS/BSOB ratio can be used as ultrasonographic markers to predict the normal development of the fetal posterior fossa.
ISSN:0091-2751
1097-0096
DOI:10.1002/jcu.23057