Do essential oils from plants occurring in the Brazilian Caatinga biome present antifungal potential against dermatophytoses? A systematic review

The Caatinga is an exclusively Brazilian biome where semiarid climatic conditions promote singularities in adaptive biodiversity. Many aromatic species are found in this region possessing antifungal properties, which are attributed to their essential oils. Thus, we questioned whether essential plant...

Full description

Saved in:
Bibliographic Details
Published in:Applied microbiology and biotechnology 2021-09, Vol.105 (18), p.6559-6578
Main Authors: Pereira, Fillipe de Oliveira, Teixeira, Anna Paula de Castro, de Medeiros, Francinalva Dantas
Format: Article
Language:English
Subjects:
Analysis
Antifungal activity
Biodiversity
Biomedical and Life Sciences
Biomes
Biotechnology
Climatic conditions
Dermatophyte fungi
Dermatophytes
Ecosystems
Essences and essential oils
Essential oils
Fungi
Fungicides
Identification and classification
In vitro methods and tests
Keratinophilic fungi
Ketoconazole
Lamiaceae
Life Sciences
Microbial Genetics and Genomics
Microbiology
Mini-Review
Oils & fats
Properties
Terbinafine
Verbenaceae
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The Caatinga is an exclusively Brazilian biome where semiarid climatic conditions promote singularities in adaptive biodiversity. Many aromatic species are found in this region possessing antifungal properties, which are attributed to their essential oils. Thus, we questioned whether essential plant oils found in the Caatinga present anti-dermatophytic potential. Dermatophytes are keratinophilic fungi that cause one of the most prevalent mycoses globally, skin infections known as dermatophytoses ( tineas ). Here, we provide a comprehensive report of the available published information, analyzing the methods used to evaluate the antifungal activity, verifying the quality of the evidence and possible clinical applications, and discussing research trends in this area. The plants studied concentrated in the genera Croton (Euphorbiaceae), Lippia (Verbenaceae), Piper (Piperaceae), and Mentha (Lamiaceae). All of the studies used in vitro tests to analyze antifungal potential, and little evidence was ascertained concerning the mechanism of antifungal action. In addition, the essential oils also evidenced drug modifying activity of conventional antifungal drugs (Ketoconazole and Terbinafine). We believe that the anti-dermatophyte potential of plant essential oils occurring within the Caatinga is underestimated and that this review will encourage future chemical-pharmacological investigations into the plants within this biome. Key points • The essential oils from plants occurring in the Caatinga Biome present unknown anti-dermatophyte potential. • The studies against dermatophyte fungi concentrate on the families Lamiaceae and Verbenaceae. • In vitro assays were used to assess the anti-dermatophyte potential of the essential oils. Graphical abstract
ISSN:0175-7598
1432-0614
DOI:10.1007/s00253-021-11530-5