PVC grafted zinc oxide nanoparticles as an inhospitable surface to microbes

Antimicrobial Polyvinyl chloride (PVC) was obtained by covalent bonding of zinc oxide nanoparticles, which have gained important achievements in antimicrobial fields because of their auspicious properties. This was achieved by grafting mercaptopropyltrimethoxysilane onto PVC, followed by the growth...

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Bibliographic Details
Published in:Materials Science & Engineering C 2021-09, Vol.128, p.112290-112290, Article 112290
Main Authors: Donnadio, Anna, Roscini, Luca, Di Michele, Alessandro, Corazzini, Valentina, Cardinali, Gianluigi, Ambrogi, Valeria
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Antimicrobial and antibiofilm activity
Covalence
Flowers
Grafted nanoparticles
Injury prevention
Materials science
Medical devices
Microorganisms
Morphology
Nanoparticles
Nosocomial infections
Polymers
Polyvinyl chloride
Risk management
Risk reduction
Surface modification
Tuning
Zinc oxide
Zinc oxides
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Summary:Antimicrobial Polyvinyl chloride (PVC) was obtained by covalent bonding of zinc oxide nanoparticles, which have gained important achievements in antimicrobial fields because of their auspicious properties. This was achieved by grafting mercaptopropyltrimethoxysilane onto PVC, followed by the growth of zinc oxide nanoparticles covalently bonded on the polymer surface. In this study, the relationship between the physicochemical features of modified-surface PVC and antimicrobial activity on Staphylococcus aureus and Candida albicans was investigated. Zinc oxide with controllable morphologies (rods, rod flowers, and petal flowers) was synthesized on the polymer surface by tuning merely base-type and concentration using a hydrothermal process. The antimicrobial activity was more pronounced for rod flower morphology, because of their differences in microscopic parameters such as specific Zn-polar planes. This work provides an important hint for the safe use of PVC for biomedical devices by the structure surface tuning without injuring polymer bulk properties and a reduced risk of the covalently bonded nanoparticle dispersion in the host and the environment. [Display omitted] •The PVC surface was homogeneously covered with ZnO nanoparticles.•ZnO particles with different morphology were covalently attached on the PVC.•The PVC coated film showed both antibacterial and antifungal activities.•The PVC coated film showed antibiofilm activity.•Reduced risk of nanoparticle dispersion.
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2021.112290