Postoperative direct‐acting antiviral treatment after liver resection in patients with hepatitis C virus‐related hepatocellular carcinoma

Aim We investigated effects of direct‐acting antiviral (DAA)–induced sustained virological response (SVR) after liver resection in patients with hepatitis C virus (HCV)–related hepatocellular carcinoma (HCC) for postoperative recurrence and survival. Methods Surgical outcomes in 18 patients with pos...

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Bibliographic Details
Published in:Hepatology research 2021-11, Vol.51 (11), p.1102-1114
Main Authors: Tanaka, Shogo, Shinkawa, Hiroji, Tamori, Akihiro, Takemura, Shigekazu, Uchida‐Kobayashi, Sawako, Amano, Ryosuke, Kimura, Kenjiro, Ohira, Go, Nishio, Kohei, Tauchi, Jun, Kinoshita, Masahiko, Kawada, Norifumi, Kubo, Shoji
Format: Article
Language:English
Subjects:
antiviral agents
Bilirubin
carcinoma
Hepatitis
Hepatitis C
hepatocellular
Hepatocellular carcinoma
immunotherapy
Liver
Liver cancer
Patients
Risk factors
Surgery
Surgical outcomes
Survival
Tumors
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Summary:Aim We investigated effects of direct‐acting antiviral (DAA)–induced sustained virological response (SVR) after liver resection in patients with hepatitis C virus (HCV)–related hepatocellular carcinoma (HCC) for postoperative recurrence and survival. Methods Surgical outcomes in 18 patients with postoperative DAA‐induced SVR (HCC‐DAA group) were compared with those in 23 patients with preoperative DAA‐induced SVR (DAA‐HCC group) and those in 10 patients who did not receive DAA therapy (control group). Patients who received DAA therapy >1 year after surgery and those with recurrence
ISSN:1386-6346
1872-034X
DOI:10.1111/hepr.13709