Meta-Analysis of Percutaneous Coronary Intervention of Chronic Total Occlusions

All-cause mortality and cardiac mortality were comparable between CTO-PCI and OMT groups at 1-year (RR: 1.70; 95% CI: 0.50 to 5.80; p = 0.40; and RR: 1.77; 95% CI: 0.19 to 16.06; p = 0.61) and at 4-year follow-up (RR: 1.14; 95% CI: 0.38 to 3.40; p = 0.81; and RR: 2.05; 95% CI: 0.8 to 5.28; p = 0.14)...

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Bibliographic Details
Published in:The American journal of cardiology 2021-11, Vol.159, p.148-151
Main Authors: Krittanawong, Chayakrit, Virk, Hafeez Hassan, Mhanna, Mohammed, Wang, Zhen, Poommipanit, Paul, Jneid, Hani
Format: Article
Language:English
Subjects:
Angioplasty
Coronary vessels
Meta-analysis
Mortality
Patient satisfaction
Stents
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Summary:All-cause mortality and cardiac mortality were comparable between CTO-PCI and OMT groups at 1-year (RR: 1.70; 95% CI: 0.50 to 5.80; p = 0.40; and RR: 1.77; 95% CI: 0.19 to 16.06; p = 0.61) and at 4-year follow-up (RR: 1.14; 95% CI: 0.38 to 3.40; p = 0.81; and RR: 2.05; 95% CI: 0.8 to 5.28; p = 0.14). [...]MI risk was comparable between the two groups at 1 and 4-year follow up (RR: 1.01; 95% CI: 0.43 to 2.36; p = 0.98) and (RR: 1.46; 95% CI: 0.75 to 2.87; p = 0.27) respectively. [...]we were unable to evaluate for overall MACE, as its definition varied across the included studies. [...]our meta-analysis did not demonstrate superior hard clinical outcomes with CTO-PCI revascularization as compared with OMT alone at short- and long-term follow-up.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2021.08.011