Safety and efficacy of minimalist transcatheter aortic valve implantation using a new-generation balloon-expandable transcatheter heart valve in bicuspid and tricuspid aortic valves

Background Bicuspid aortic valve may be associated with increased complications during transcatheter aortic valve implantation (TAVI). Aims Compare balloon-expandable transcatheter heart valve (THV) safety and efficacy in severe tricuspid (TAV) and bicuspid (BAV) aortic stenosis. Methods Transfemora...

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Bibliographic Details
Published in:Clinical research in cardiology 2021-12, Vol.110 (12), p.1993-2006
Main Authors: Michel, Jonathan M., Frangieh, Antonio H., Giacoppo, Daniele, Alvarez-Covarrubias, Hector A., Pellegrini, Costanza, Rheude, Tobias, Deutsch, Oliver, Mayr, N. Patrick, Rumpf, P. Moritz, Stähli, Barbara E., Kastrati, Adnan, Schunkert, Heribert, Xhepa, Erion, Joner, Michael, Kasel, A. Markus
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aorta
Aortic stenosis
Aortic valve
Aortic Valve - surgery
Aortic Valve Stenosis - diagnosis
Aortic Valve Stenosis - surgery
Balloon treatment
Calcification
Cardiology
Complications
Computed tomography
Confidence intervals
Congestive heart failure
Female
Follow-Up Studies
Heart Valve Prosthesis
Heart valves
Humans
Implantation
Male
Medicine
Medicine & Public Health
Mortality
Multidetector Computed Tomography - methods
Original Paper
Prosthesis Design
Retrospective Studies
Safety
Thromboembolism
Thrombosis
Time Factors
Transcatheter Aortic Valve Replacement - methods
Treatment Outcome
Tricuspid Valve - surgery
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Summary:Background Bicuspid aortic valve may be associated with increased complications during transcatheter aortic valve implantation (TAVI). Aims Compare balloon-expandable transcatheter heart valve (THV) safety and efficacy in severe tricuspid (TAV) and bicuspid (BAV) aortic stenosis. Methods Transfemoral TAVI was performed in 743 patients (Jan 2014–June 2019) using the SAPIEN 3 THV. Aortic valve morphology was determined using computed tomography. Valve Academic Research Consortium-2 (VARC-2) derived safety and efficacy endpoints at 1 year were evaluated. Results BAV patients ( n  = 78), were younger (77 [72, 81] vs. 81 [78, 85] years, p  
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-021-01935-7