Antioxidant properties and inhibition of lipid formation in 3T3‐L1 adipocytes of in vitro digested mageu, a commercial sample

Mageu is a fermented, non‐alcoholic maize‐derived product unique to southern Africa. The aim of this study was to identify the health benefits of a polyphenolic extract of commercially produced mageu related to the antioxidant properties and effects on lipid accumulation in differentiated 3T3‐L1 adi...

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Bibliographic Details
Published in:Journal of food biochemistry 2021-10, Vol.45 (10), p.e13929-n/a
Main Authors: Nathu, Haleema, Mbuyama, Kabuzi R., Adarkwah‐Yiadom, Martin, Serem, June C., Ibrahim, Mohammed Auwal, Duodu, Kwaku G., Gaspar, Anabella R. M., Bester, Megan J.
Format: Article
Language:English
Subjects:
antioxidant
anti‐lipogenic
bioaccessibility
in vitro digestion
mageu
phenolic acids
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Summary:Mageu is a fermented, non‐alcoholic maize‐derived product unique to southern Africa. The aim of this study was to identify the health benefits of a polyphenolic extract of commercially produced mageu related to the antioxidant properties and effects on lipid accumulation in differentiated 3T3‐L1 adipocytes. A pooled sample of mageu Number 1 brand (original non‐flavored) was subjected to in vitro gastroduodenal digestion (GDD). Reverse phase high‐performance liquid chromatography of unfractionated undigested (UD) and GDD mageu revealed that with digestion there was an increased extraction of 1.2, 1.83, 1.45, 4.86, and 3.17‐fold of caffeic acid, 3,4‐dihydroxybenzoic acid, p‐coumaric acid, 4 hydroxybenzoic acid and ferulic acid, respectively. An associated increase in the total phenolic acid content and antioxidant activity in the
ISSN:0145-8884
1745-4514
DOI:10.1111/jfbc.13929