Gut Microbiota is an Important Source of Bacteriocins and Their In Situ Expression Can Be Explored for Treatment of Bacterial Infections

Bacteriocins are interesting natural antimicrobial peptides that could be deployed quickly to combat certain antimicrobial-resistant bacterial infections. These molecules could be used in conjunction with traditional antibiotics, or even to replace them in some circumstances. To strengthen the conce...

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Bibliographic Details
Published in:Probiotics and antimicrobial proteins 2021-12, Vol.13 (6), p.1759-1765
Main Author: Drider, Djamel
Format: Article
Language:English
Subjects:
Antibiotics
Antimicrobial Peptides
Applied Microbiology
Bacteria
Bacterial infections
Bacterial Infections - therapy
Bacteriocins
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Gastrointestinal Microbiome
Humans
Intestinal microflora
Microbiology
Microbiota
Nutrition
Protein Science
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Summary:Bacteriocins are interesting natural antimicrobial peptides that could be deployed quickly to combat certain antimicrobial-resistant bacterial infections. These molecules could be used in conjunction with traditional antibiotics, or even to replace them in some circumstances. To strengthen the concept of “bacteriocinotherapy,” we discuss here the benefits associated with production in situ of bacteriocins by commensal bacteria. This on sites production capacity could augment the gut microbiota global resistance plan and provide a backup for bacterial infection treatments.
ISSN:1867-1306
1867-1314
DOI:10.1007/s12602-021-09843-y