Lymphocytoma cutis (cutaneous B‐cell pseudolymphoma): study of 102 cases with emphasis on the histological characteristics and immunohistochemistry of the miliarial type

Background Lymphocytoma cutis (LC) is a benign reactive lymphoproliferative B‐cell process. It has two variants: localized type with solitary lesions and miliarial type with numerous lesions. The objective was to investigate the characteristics of LC with emphasis on the miliarial type. Methods Retr...

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Bibliographic Details
Published in:International journal of dermatology 2022-03, Vol.61 (3), p.316-323
Main Authors: Villalobos‐Ayala, Romina A., Espinoza‐Gurrola, América A., Guevara‐Gutiérrez, Elizabeth, Solís‐Ledesma, Guillermo, Ramos‐Suárez, Marina, Rodríguez‐Castellanos, Marco A., Tlacuilo‐Parra, Alberto
Format: Article
Language:English
Subjects:
CD20 antigen
Corticoids
Corticosteroids
Diagnosis, Differential
Evolution
Female
Humans
Immunohistochemistry
Lesions
Light chains
Lymphocytes
Lymphoma
Middle Aged
Patients
Pseudolymphoma - diagnosis
Retrospective Studies
Skin Neoplasms
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Summary:Background Lymphocytoma cutis (LC) is a benign reactive lymphoproliferative B‐cell process. It has two variants: localized type with solitary lesions and miliarial type with numerous lesions. The objective was to investigate the characteristics of LC with emphasis on the miliarial type. Methods Retrospective study, patients with clinical and histopathological diagnosis of LC were included. Age, sex, evolution time, affected site, and type of treatment were investigated. In miliarial‐type LC, the histological and immunohistochemical characteristics were also investigated. Results In an 18‐year period, there were 102 patients found with LC: 72 (71%) corresponded to females, the median age was 45 years, the median evolution time was 4 months, and the face was the most predominant affected area in 81 (79%) cases. Localized‐type LC corresponded to 88 (86%) cases, and miliarial type in 14 (14%). The most common treatment was surgery, which was used in 32 (31%) patients, all of whom had localized type (P 
ISSN:0011-9059
1365-4632
DOI:10.1111/ijd.15909