Long-term renal outcomes of mesangial proliferative lupus nephritis in Chinese patients

Objective This study aimed to explore the long-term outcomes of mesangial proliferative lupus nephritis (LN class II) and the factors associated with its relapse and histological transformation in Chinese patients. Methods 104 SLE patients with biopsy-proven LN class II were included and divided int...

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Bibliographic Details
Published in:Clinical rheumatology 2022-02, Vol.41 (2), p.429-436
Main Authors: Wang, Shaofan, Chen, Duqun, Zuo, Ke, Xu, Feng, Hu, Weixin
Format: Article
Language:English
Subjects:
Biopsy
China
End-stage renal disease
Glucocorticoids
Hematuria
Humans
Kidney
Kidney diseases
Lupus
Lupus nephritis
Lupus Nephritis - drug therapy
Medicine
Medicine & Public Health
Nephritis
Original Article
Proliferative kidney disease
Proteinuria
Remission
Retrospective Studies
Rheumatology
Risk factors
Systemic lupus erythematosus
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Summary:Objective This study aimed to explore the long-term outcomes of mesangial proliferative lupus nephritis (LN class II) and the factors associated with its relapse and histological transformation in Chinese patients. Methods 104 SLE patients with biopsy-proven LN class II were included and divided into proteinuria group (proteinuria ≥ 0.4 g/24 h, with or without microscopic hematuria) and hematuria group (microscopic hematuria with proteinuria 
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-021-05909-y