Reference intervals for end-tidal carbon monoxide of preterm neonates

Objectives We constructed reference intervals for end-tidal carbon monoxide (ETCOc) levels of neonates 28 0/7 to 34 6/7 weeks gestation in order to assess hemolytic rate. Study design This is a prospective four-NICU study in Bangkok, Thailand, and Utah, USA. Results Of 226 attempted measurements, 92...

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Bibliographic Details
Published in:Journal of perinatology 2022-01, Vol.42 (1), p.116-120
Main Authors: Pakdeeto, Sasikarn, Christensen, Thomas R., Bahr, Timothy M., Gerday, Erick, Sheffield, Mark J., Christensen, Kyle S., Supapannachart, Sarayut, Nuntnarumit, Pracha, Sukwiset, Saranya, Ohls, Robin K., Christensen, Robert D.
Format: Article
Language:English
Subjects:
692/53/2421
692/53/2422
692/699/1541
Birth
Breath Tests
Carbon monoxide
Carbon Monoxide - analysis
Female
Gestation
Hemolysis
Humans
Infant, Newborn
Infant, Premature
Intensive care
Intervals
Medicine
Medicine & Public Health
Neonatal care
Neonates
Newborn babies
Pediatric Surgery
Pediatrics
Pregnancy
Premature birth
Prospective Studies
Reference Values
Thailand
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Summary:Objectives We constructed reference intervals for end-tidal carbon monoxide (ETCOc) levels of neonates 28 0/7 to 34 6/7 weeks gestation in order to assess hemolytic rate. Study design This is a prospective four-NICU study in Bangkok, Thailand, and Utah, USA. Results Of 226 attempted measurements, 92% were successful. Values from day 1 through 28 were charted and upper (>95th percentile) reference interval limits calculated. During the entire 28 days, the ETCOc upper reference intervals from babies in Bangkok were higher than those in Utah ( p   0.1). Similar to term neonates, preterm neonates in Bangkok and Utah had higher ETCOc values during the first 48 h after birth than thereafter ( p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-021-01207-2