The cross-sectional association of cognition with diabetic peripheral and autonomic neuropathy—The GRADE study

Studies examining whether measures of cognition are related to the presence of diabetic peripheral neuropathy (DPN) and/or cardiovascular autonomic neuropathy (CAN) are lacking, as are data regarding factors potentially explaining such associations. Participants were from the Glycemia Reduction Appr...

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Published in:Journal of diabetes and its complications 2021-12, Vol.35 (12), p.108047-108047, Article 108047
Main Authors: Barzilay, Joshua I., Ghosh, Alokananda, Busui, Rodica Pop, Ahmann, Andrew, Balasubramanyam, Ashok, Banerji, Mary Ann, Cohen, Robert M., Green, Jennifer, Ismail-Beigi, Faramarz, Martin, Catherine L., Seaquist, Elizabeth, Luchsinger, José A.
Format: Article
Language:English
Subjects:
Aged
Animal cognition
Autonomic Nervous System Diseases - etiology
Blood pressure
Body mass index
Cardiovascular autonomic neuropathy
Cardiovascular Diseases - complications
Cognition
Cognition Disorders - diagnosis
Cognition Disorders - etiology
Cognitive tests
Creatinine
Cross-Sectional Studies
Diabetes
Diabetes Mellitus, Type 2 - complications
Diabetic Neuropathies - complications
Diabetic peripheral neuropathy
Female
Glucose
Humans
Hyperglycemia
Hypotheses
Male
Middle Aged
Peripheral Nervous System Diseases - etiology
Quality of life
Questionnaires
Regression analysis
Urine
Variables
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Summary:Studies examining whether measures of cognition are related to the presence of diabetic peripheral neuropathy (DPN) and/or cardiovascular autonomic neuropathy (CAN) are lacking, as are data regarding factors potentially explaining such associations. Participants were from the Glycemia Reduction Approaches in Diabetes Study (GRADE) that examined 5047 middle-aged people with type 2 diabetes of
ISSN:1056-8727
1873-460X
DOI:10.1016/j.jdiacomp.2021.108047