Chemical composition and antimicrobial activity of the leaf essential oil of Ravenia spectabilis Engl. (Rutaceae)

Ravenia spectabilis Engl. belongs to the family Rutaceae is known to possess several biologically active phytomolecules. This study was planned to investigate the chemical composition and antimicrobial activity of the leaf essential oil of R. spectabilis. The hydrodistillation of fresh leaves of R....

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Bibliographic Details
Published in:Natural product research 2022-09, Vol.36 (17), p.4433-4436
Main Authors: Singh, Swati, Kurmi, Alka, Singh, Munmun Kumar, Kashyap, Praveen Kumar, Tandon, Sudeep, Chauhan, Amit, Padalia, Rajendra Chandra, Saikia, Dharmendra, Verma, Ram Swaroop
Format: Article
Language:English
Subjects:
3-Carene
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Biological activity
Chemical composition
Chromatography
Drug resistance
Essential oils
Flame ionization detectors
Gas chromatography
Ionization
Leaves
Mass spectrometry
Mass spectroscopy
Methicillin
Myrcene
Oils & fats
Ravenia
Rutaceae
Sabinene
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus infections
α-Pinene
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Summary:Ravenia spectabilis Engl. belongs to the family Rutaceae is known to possess several biologically active phytomolecules. This study was planned to investigate the chemical composition and antimicrobial activity of the leaf essential oil of R. spectabilis. The hydrodistillation of fresh leaves of R. spectabilis gave 0.19 ± 0.02% essential oil. The resulting essential oil was analysed by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Altogether, thirty-one constituents forming 97.6 ± 1.72% of the total oil composition were identified. Major components of the oil were sabinene (60.8 ± 0.36%), α-pinene (5.4 ± 0.30%), myrcene (4.8 ± 0.25%), δ-3-carene (4.7 ± 0.62%) and β-pinene (4.3 ± 0.17%). The in-vitro antimicrobial potential of the oil was examined against eight human pathogenic bacterial and fungal strains. The essential oil showed significant activity against Staphylococcus aureus, Staphylococcus epidermidis, methicillin-resistant Staphylococcus aureus, methicillin-resistant Staphylococcus epidermidis, Candida albicans, and Candida kefyr. This is the first report on R. spectabilis leaf essential oil composition and its antimicrobial activity. The essential oil could be a promising natural source of sabinene and antimicrobial for developing new phytotherapeutics.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2021.1981312