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Coping response and family communication of cancer risk in men harboring a BRCA mutation: A mixed methods study
Objective Providing genetic counseling and genetic testing to at‐risk blood relatives (cascade screening) is important for improving BRCA cancer outcomes. Intra‐familial communication of risk is critical for cascade screening efforts yet relatively little is known about men's role in communicat...
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| Published in: | Psycho-oncology (Chichester, England) England), 2022-03, Vol.31 (3), p.486-495 |
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| cites | cdi_FETCH-LOGICAL-c3491-9c7978d748ddbe97685ab3e99eb79070d9e292681d7e1fb8ea0cea3e2b504fcd3 |
| container_end_page | 495 |
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| container_title | Psycho-oncology (Chichester, England) |
| container_volume | 31 |
| creator | Dwyer, Andrew A. Hesse‐Biber, Sharlene Shea, Hannah Zeng, Ziwei Yi, Shiya |
| description | Objective
Providing genetic counseling and genetic testing to at‐risk blood relatives (cascade screening) is important for improving BRCA cancer outcomes. Intra‐familial communication of risk is critical for cascade screening efforts yet relatively little is known about men's role in communicating BRCA risk. We sought to examine men's coping response to their BRCA status and intra‐familial communication of risk to inform the development of tailored interventions that could promote cascade screening.
Methods
We employed a sequential mixed‐methods design. First, we measured coping response (quantitative) using the Multidimensional Impact of Cancer Risk Assessment (MICRA). MICRA scores were compared between BRCA+ men, BRCA− men and BRCA+ women. Subsequently, we used template analysis to analyze qualitative interviews exploring coping and intra‐familial communication of risk. The Theory of Planned Behavior (TPB) served as a guiding framework for identifying intervention targets.
Results
BRCA+ men (n = 36) had significantly higher levels of distress (p |
| doi_str_mv | 10.1002/pon.5831 |
| format | article |
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Providing genetic counseling and genetic testing to at‐risk blood relatives (cascade screening) is important for improving BRCA cancer outcomes. Intra‐familial communication of risk is critical for cascade screening efforts yet relatively little is known about men's role in communicating BRCA risk. We sought to examine men's coping response to their BRCA status and intra‐familial communication of risk to inform the development of tailored interventions that could promote cascade screening.
Methods
We employed a sequential mixed‐methods design. First, we measured coping response (quantitative) using the Multidimensional Impact of Cancer Risk Assessment (MICRA). MICRA scores were compared between BRCA+ men, BRCA− men and BRCA+ women. Subsequently, we used template analysis to analyze qualitative interviews exploring coping and intra‐familial communication of risk. The Theory of Planned Behavior (TPB) served as a guiding framework for identifying intervention targets.
Results
BRCA+ men (n = 36) had significantly higher levels of distress (p < 0.001), uncertainty (p < 0.001) and negative experiences (p < 0.05) compared to BRCA− male counterparts (n = 23). BRCA+ men had significantly lower distress (p < 0.001) and uncertainty (p < 0.001) than BRCA+ women (n = 406). Qualitative analysis of in‐depth interviews with BRCA+ men (n = 35) identified promoters and barriers to active coping response and intra‐familial communication of risk. Mapping results onto the TPB identified targets for tailoring person‐centered approaches for men addressing beliefs/attitude, subjective norms, and perceived behavioral control.
Conclusions
Men and women appear to have different coping responses to learning their BRCA status. Developing tailored (sex‐based), theory informed interventions may help promote intra‐familial communication of BRCA risk and support cascade screening.</description><identifier>ISSN: 1057-9249</identifier><identifier>EISSN: 1099-1611</identifier><identifier>DOI: 10.1002/pon.5831</identifier><identifier>PMID: 34582073</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>BRCA mutation ; Breast cancer ; Cancer ; cascade screening ; Communication ; Coping ; Genetic counseling ; genetic risk ; Genetic testing ; hereditary breast ovarian cancer ; Intervention ; Interviews ; Mapping ; Mens health ; Mixed methods research ; Negative experiences ; oncology ; Ovarian cancer ; Patient-centered care ; Perceived control ; Psychological distress ; Qualitative research ; Relatives ; Risk assessment ; Theory of Planned Behavior ; Uncertainty ; Women</subject><ispartof>Psycho-oncology (Chichester, England), 2022-03, Vol.31 (3), p.486-495</ispartof><rights>2021 John Wiley & Sons Ltd.</rights><rights>2022 John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3491-9c7978d748ddbe97685ab3e99eb79070d9e292681d7e1fb8ea0cea3e2b504fcd3</citedby><cites>FETCH-LOGICAL-c3491-9c7978d748ddbe97685ab3e99eb79070d9e292681d7e1fb8ea0cea3e2b504fcd3</cites><orcidid>0000-0002-7023-6794</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923,30997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34582073$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dwyer, Andrew A.</creatorcontrib><creatorcontrib>Hesse‐Biber, Sharlene</creatorcontrib><creatorcontrib>Shea, Hannah</creatorcontrib><creatorcontrib>Zeng, Ziwei</creatorcontrib><creatorcontrib>Yi, Shiya</creatorcontrib><title>Coping response and family communication of cancer risk in men harboring a BRCA mutation: A mixed methods study</title><title>Psycho-oncology (Chichester, England)</title><addtitle>Psychooncology</addtitle><description>Objective
Providing genetic counseling and genetic testing to at‐risk blood relatives (cascade screening) is important for improving BRCA cancer outcomes. Intra‐familial communication of risk is critical for cascade screening efforts yet relatively little is known about men's role in communicating BRCA risk. We sought to examine men's coping response to their BRCA status and intra‐familial communication of risk to inform the development of tailored interventions that could promote cascade screening.
Methods
We employed a sequential mixed‐methods design. First, we measured coping response (quantitative) using the Multidimensional Impact of Cancer Risk Assessment (MICRA). MICRA scores were compared between BRCA+ men, BRCA− men and BRCA+ women. Subsequently, we used template analysis to analyze qualitative interviews exploring coping and intra‐familial communication of risk. The Theory of Planned Behavior (TPB) served as a guiding framework for identifying intervention targets.
Results
BRCA+ men (n = 36) had significantly higher levels of distress (p < 0.001), uncertainty (p < 0.001) and negative experiences (p < 0.05) compared to BRCA− male counterparts (n = 23). BRCA+ men had significantly lower distress (p < 0.001) and uncertainty (p < 0.001) than BRCA+ women (n = 406). Qualitative analysis of in‐depth interviews with BRCA+ men (n = 35) identified promoters and barriers to active coping response and intra‐familial communication of risk. Mapping results onto the TPB identified targets for tailoring person‐centered approaches for men addressing beliefs/attitude, subjective norms, and perceived behavioral control.
Conclusions
Men and women appear to have different coping responses to learning their BRCA status. Developing tailored (sex‐based), theory informed interventions may help promote intra‐familial communication of BRCA risk and support cascade screening.</description><subject>BRCA mutation</subject><subject>Breast cancer</subject><subject>Cancer</subject><subject>cascade screening</subject><subject>Communication</subject><subject>Coping</subject><subject>Genetic counseling</subject><subject>genetic risk</subject><subject>Genetic testing</subject><subject>hereditary breast ovarian cancer</subject><subject>Intervention</subject><subject>Interviews</subject><subject>Mapping</subject><subject>Mens health</subject><subject>Mixed methods research</subject><subject>Negative experiences</subject><subject>oncology</subject><subject>Ovarian cancer</subject><subject>Patient-centered care</subject><subject>Perceived control</subject><subject>Psychological distress</subject><subject>Qualitative research</subject><subject>Relatives</subject><subject>Risk assessment</subject><subject>Theory of Planned Behavior</subject><subject>Uncertainty</subject><subject>Women</subject><issn>1057-9249</issn><issn>1099-1611</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><recordid>eNp10UFLHDEUwPFQlGq3hX4CCXjpZdYkM5lMvOlSW2HpirTnkEneaHQmWZMZ6n57s6tVEHrKO_z4E95D6Cslc0oIO1kHP-dNST-gQ0qkLGhN6d525qKQrJIH6FNKd4RkLOuP6KCseMOIKA9RWIS18zc4QsqRBFh7izs9uH6DTRiGyTujRxc8Dh022huIOLp0j53HA3h8q2Mb4rag8fn14gwP07jzpzjP7hFsZuNtsAmncbKbz2i_032CLy_vDP25-P578bNYrn5cLs6WhSkrSQtphBSNFVVjbQtS1A3XbQlSQiskEcRKYJLVDbUCaNc2oIkBXQJrOak6Y8sZ-vbcXcfwMEEa1eCSgb7XHsKUFONCVDXnrMr0-B29C1P0-XeK1RWRQjacvwVNDClF6NQ6ukHHjaJEbY-g8v7U9giZHr0Ep3YA-wr_bT2D4hn8dT1s_htSV6tfu-ATDBeQdQ</recordid><startdate>202203</startdate><enddate>202203</enddate><creator>Dwyer, Andrew A.</creator><creator>Hesse‐Biber, Sharlene</creator><creator>Shea, Hannah</creator><creator>Zeng, Ziwei</creator><creator>Yi, Shiya</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7023-6794</orcidid></search><sort><creationdate>202203</creationdate><title>Coping response and family communication of cancer risk in men harboring a BRCA mutation: A mixed methods study</title><author>Dwyer, Andrew A. ; Hesse‐Biber, Sharlene ; Shea, Hannah ; Zeng, Ziwei ; Yi, Shiya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3491-9c7978d748ddbe97685ab3e99eb79070d9e292681d7e1fb8ea0cea3e2b504fcd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>BRCA mutation</topic><topic>Breast cancer</topic><topic>Cancer</topic><topic>cascade screening</topic><topic>Communication</topic><topic>Coping</topic><topic>Genetic counseling</topic><topic>genetic risk</topic><topic>Genetic testing</topic><topic>hereditary breast ovarian cancer</topic><topic>Intervention</topic><topic>Interviews</topic><topic>Mapping</topic><topic>Mens health</topic><topic>Mixed methods research</topic><topic>Negative experiences</topic><topic>oncology</topic><topic>Ovarian cancer</topic><topic>Patient-centered care</topic><topic>Perceived control</topic><topic>Psychological distress</topic><topic>Qualitative research</topic><topic>Relatives</topic><topic>Risk assessment</topic><topic>Theory of Planned Behavior</topic><topic>Uncertainty</topic><topic>Women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dwyer, Andrew A.</creatorcontrib><creatorcontrib>Hesse‐Biber, Sharlene</creatorcontrib><creatorcontrib>Shea, Hannah</creatorcontrib><creatorcontrib>Zeng, Ziwei</creatorcontrib><creatorcontrib>Yi, Shiya</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Psycho-oncology (Chichester, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dwyer, Andrew A.</au><au>Hesse‐Biber, Sharlene</au><au>Shea, Hannah</au><au>Zeng, Ziwei</au><au>Yi, Shiya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coping response and family communication of cancer risk in men harboring a BRCA mutation: A mixed methods study</atitle><jtitle>Psycho-oncology (Chichester, England)</jtitle><addtitle>Psychooncology</addtitle><date>2022-03</date><risdate>2022</risdate><volume>31</volume><issue>3</issue><spage>486</spage><epage>495</epage><pages>486-495</pages><issn>1057-9249</issn><eissn>1099-1611</eissn><abstract>Objective
Providing genetic counseling and genetic testing to at‐risk blood relatives (cascade screening) is important for improving BRCA cancer outcomes. Intra‐familial communication of risk is critical for cascade screening efforts yet relatively little is known about men's role in communicating BRCA risk. We sought to examine men's coping response to their BRCA status and intra‐familial communication of risk to inform the development of tailored interventions that could promote cascade screening.
Methods
We employed a sequential mixed‐methods design. First, we measured coping response (quantitative) using the Multidimensional Impact of Cancer Risk Assessment (MICRA). MICRA scores were compared between BRCA+ men, BRCA− men and BRCA+ women. Subsequently, we used template analysis to analyze qualitative interviews exploring coping and intra‐familial communication of risk. The Theory of Planned Behavior (TPB) served as a guiding framework for identifying intervention targets.
Results
BRCA+ men (n = 36) had significantly higher levels of distress (p < 0.001), uncertainty (p < 0.001) and negative experiences (p < 0.05) compared to BRCA− male counterparts (n = 23). BRCA+ men had significantly lower distress (p < 0.001) and uncertainty (p < 0.001) than BRCA+ women (n = 406). Qualitative analysis of in‐depth interviews with BRCA+ men (n = 35) identified promoters and barriers to active coping response and intra‐familial communication of risk. Mapping results onto the TPB identified targets for tailoring person‐centered approaches for men addressing beliefs/attitude, subjective norms, and perceived behavioral control.
Conclusions
Men and women appear to have different coping responses to learning their BRCA status. Developing tailored (sex‐based), theory informed interventions may help promote intra‐familial communication of BRCA risk and support cascade screening.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>34582073</pmid><doi>10.1002/pon.5831</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-7023-6794</orcidid></addata></record> |
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| ispartof | Psycho-oncology (Chichester, England), 2022-03, Vol.31 (3), p.486-495 |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); Wiley:Jisc Collections:Wiley Read and Publish Open Access 2024-2025 (reading list) |
| subjects | BRCA mutation Breast cancer Cancer cascade screening Communication Coping Genetic counseling genetic risk Genetic testing hereditary breast ovarian cancer Intervention Interviews Mapping Mens health Mixed methods research Negative experiences oncology Ovarian cancer Patient-centered care Perceived control Psychological distress Qualitative research Relatives Risk assessment Theory of Planned Behavior Uncertainty Women |
| title | Coping response and family communication of cancer risk in men harboring a BRCA mutation: A mixed methods study |
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