Vitamin A supplementation in very-preterm or very-low-birth-weight infants to prevent morbidity and mortality: a systematic review and meta-analysis of randomized trials

A previous systematic review showed that intramuscular vitamin A supplementation reduced the risk of bronchopulmonary dysplasia (BPD) in very-low-birth-weight (VLBW) infants. However, more recent studies have questioned this finding. Our objective was to synthesize current evidence on vitamin A supp...

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Bibliographic Details
Published in:The American journal of clinical nutrition 2021-12, Vol.114 (6), p.2084-2096
Main Authors: Rakshasbhuvankar, Abhijeet A, Pillow, J Jane, Simmer, Karen N, Patole, Sanjay K
Format: Article
Language:English
Subjects:
Birth weight
bronchopulmonary dysplasia
Bronchopulmonary Dysplasia - prevention & control
chronic lung disease
Dietary Supplements
Dysplasia
Gestational age
Humans
Infant
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Infants
Low birth weight
Meta-analysis
Morbidity
Mortality
nutrition
prematurity
Quality
Randomized Controlled Trials as Topic
Retinene
Reviews
Subgroups
Supplements
Systematic review
Vitamin A
Vitamin A - therapeutic use
vitamins
Weight
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Description
Summary:A previous systematic review showed that intramuscular vitamin A supplementation reduced the risk of bronchopulmonary dysplasia (BPD) in very-low-birth-weight (VLBW) infants. However, more recent studies have questioned this finding. Our objective was to synthesize current evidence on vitamin A supplementation in very-preterm (
ISSN:0002-9165
1938-3207
DOI:10.1093/ajcn/nqab294