The effect of heated lidocaine gel on pain reduction during transrectal ultrasound-guided prostate biopsy: a randomized-controlled study

Purpose To determine whether intrarectal local anesthesia (IRLA) with heated lidocaine gel provides pain reduction during transrectal ultrasound (TRUS)-guided prostate biopsy. Methods We conducted a randomized-controlled study with 153 participants who underwent TRUS-guided, systematic 12-core prost...

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Bibliographic Details
Published in:International urology and nephrology 2021-12, Vol.53 (12), p.2437-2443
Main Authors: Jung, Joon Se, Moon, Hee Nam, Kim, Jung Im, Bae, Sang Rak, Han, Chang Hee, Park, Bong Hee
Format: Article
Language:English
Subjects:
Aged
Anesthesia
Anesthetics, Local - administration & dosage
Biopsy
Biopsy, Large-Core Needle
Gels
Hot Temperature
Humans
Hypersensitivity
Lidocaine
Lidocaine - administration & dosage
Local anesthesia
Male
Medicine
Medicine & Public Health
Nephrology
Pain
Pain Management - methods
Pain Measurement
Prospective Studies
Prostate
Prostatic Neoplasms - pathology
Republic of Korea
Ultrasonic imaging
Ultrasonography, Interventional
Ultrasound
Urology
Urology - Original Paper
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Summary:Purpose To determine whether intrarectal local anesthesia (IRLA) with heated lidocaine gel provides pain reduction during transrectal ultrasound (TRUS)-guided prostate biopsy. Methods We conducted a randomized-controlled study with 153 participants who underwent TRUS-guided, systematic 12-core prostate biopsy from May 2018 to June 2019. These participants were divided into three test groups. Before prostate biopsy, group A (51 patients) received no local anesthesia, group B (51 patients) received IRLA with 20 mL 2% lidocaine gel stored at room temperature, and group C (51 patients) received IRLA with heated (40 ℃) 20 mL 2% lidocaine gel. Pain was assessed using the 0–10 visual analogue scale (VAS) at three time points: VAS-1: during probe insertion, VAS-2: during biopsy, VAS-3: 30 min after the procedure. Complications during and after the procedure were evaluated. Results The mean VAS-2 score was significantly lower in group C compared to groups A and B (A, 4.6; B, 4.2; and C, 3.2; p  
ISSN:0301-1623
1573-2584
DOI:10.1007/s11255-021-03006-2