Changes over time in the association between type 2 diabetes and post-discharge outcomes in decompensated chronic heart failure patients: Findings from the RICA Registry

Heart failure (HF) and diabetes are 2 strongly associated diseases. The main objective of this work was to analyze changes in the prognosis of patients with diabetes who were admitted for heart failure in 2 time periods. This work is a prospective study comparing prognosis at one year of follow-up a...

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Published in:Revista clínica espanõla (English edition) 2022-02, Vol.222 (2), p.63-72
Main Authors: Carrasco-Sánchez, F.J., Páez-Rubio, M.I., Arévalo-Lorido, J.C., Carretero-Gómez, J., Conde-Martel, A., Epelde, F., Álvarez-Rocha, P., Salamanca-Bautista, M.P., Cepeda-Rodrigo, J.M., Montero-Pérez-Barquero, M.
Format: Article
Language:English
Subjects:
Aftercare
Diabetes mellitus
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - mortality
Heart failure
Heart Failure - complications
Heart Failure - mortality
Heart Failure - therapy
Hospitalización
Hospitalization
Humans
Insuficiencia cardíaca
Mortalidad
Mortality
Patient Discharge
Patient Readmission
Prognosis
Pronóstico
Prospective Studies
Readmissions
Registries
Reingresos
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Summary:Heart failure (HF) and diabetes are 2 strongly associated diseases. The main objective of this work was to analyze changes in the prognosis of patients with diabetes who were admitted for heart failure in 2 time periods. This work is a prospective study comparing prognosis at one year of follow-up among patients with diabetes who were hospitalized for HF in either 2008–2011 or 2018. The patients are from the Spanish Society of Internal Medicine's National Heart Failure Registry (RICA, for its initials in Spanish). The primary endpoint was to analyze the composite outcome of total mortality and/or readmission due to HF in 12 months. A multivariate Cox regression model was used to evaluate the strength of association (hazard ratio [HR]) between diabetes and the outcomes between both periods. A total of 936 patients were included in the 2018 cohort, of which 446 (48%) had diabetes. The baseline characteristics of the populations from the 2 periods were similar. In patients with diabetes, the composite outcome was observed in 233 (47.5%) in the 2008–2011 cohort and 162 (36%) in the 2018 cohort [HR 1.48; 95% confidence interval (95%CI) 1.18–1.85; p 
ISSN:2254-8874
2254-8874
DOI:10.1016/j.rceng.2021.04.010