Nucleated red blood cells as a biomarker for mortality in infants and neonates requiring veno-arterial extracorporeal membrane oxygenation for cardiac disease

Introduction: Nucleated red blood cells (NRBC) are rare in the peripheral circulation of healthy individuals and their presence have been associated with mortality in adults and very low birth weight newborns, however, its value as a biomarker for mortality in infants requiring veno-arterial (VA) ex...

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Bibliographic Details
Published in:Perfusion 2023-03, Vol.38 (2), p.299-304
Main Authors: Piggott, Kurt D, Norlin, Casey, Laviolette, Cynthia, Turner, Jason, Lewis, LaTasha, Soliman, Amira, Hebert, David, Pettitt, Tim
Format: Article
Language:English
Subjects:
Adult
Biomarkers
Birth weight
Blood circulation
Coronary artery disease
Erythrocytes
Extracorporeal Membrane Oxygenation
Heart Diseases
Humans
Infant
Infant, Newborn
Infants
Lactic acid
Low birth weight
Membranes
Mortality
Neonates
Newborn babies
Oxygenation
Peripheral circulation
Retrospective Studies
Treatment Outcome
Ventricle
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Summary:Introduction: Nucleated red blood cells (NRBC) are rare in the peripheral circulation of healthy individuals and their presence have been associated with mortality in adults and very low birth weight newborns, however, its value as a biomarker for mortality in infants requiring veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) has yet to be studied. We sought to determine if NRBC can serve as a biomarker for ECMO mortality and inpatient mortality in infants requiring V-A ECMO. Methods: A single-center retrospective chart review analyzing infants
ISSN:0267-6591
1477-111X
DOI:10.1177/02676591211050607