Exercise training-induced adaptations in lung cancer patients who have undergone a lobectomy

• Published in: Experimental gerontology 2021-11, Vol.155, p.111587-111587, Article 111587
• Main Authors: Harman, Nicholas, Lazio, Michael, Hayward, Reid
• Format: Article
• Language: English
• Subjects: Cardiorespiratory fitness; Exercise; Exercise oncology; Exercise Therapy; Humans; Lobectomy; Lung cancer; Lung Neoplasms - surgery; Muscle Strength; Quality of Life
• ISSN: 0531-5565; 1873-6815
• DOI: 10.1016/j.exger.2021.111587

To determine the safety and effectiveness of a prescribed, individualized, 12-week exercise intervention on cardiorespiratory function, muscular strength, and quality of life in lung cancer patients who have undergone a lobectomy. In addition, we sought to compare the exercise training response of lung cancer patients who have undergone a lobectomy to a population of cancer patients with all other cancers in order to examine the specific effects of a lobectomy when compared to cancer patients at large. Participants were referred by a physician, and upon entry, completed an exercise-based assessment and surveys to assess various quality of life measures. Participants were divided into two groups: lung cancer patients having undergone a lobectomy (LOB, n = 9) or those diagnosed with all other cancers (AOC, n = 201). Participants underwent 12 weeks of supervised exercise based on an individualized exercise prescription. Measures of cardiorespiratory function, muscular strength, and quality of life were collected prior to the intervention and after 12 weeks of exercise training. Significant improvements to VO2peak (p