Prevalence of diabetes in people with intellectual disabilities and age‐ and gender‐matched controls: A meta‐analysis

Background This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population...

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Published in:Journal of applied research in intellectual disabilities 2022-03, Vol.35 (2), p.301-311
Main Authors: Vancampfort, Davy, Schuch, Felipe, Van Damme, Tine, Firth, Joseph, Suetani, Shuichi, Stubbs, Brendon, Van Biesen, Debbie
Format: Article
Language:English
Subjects:
Age Differences
Age groups
Aged
Anxiety
Case-Control Studies
Comorbidity
Demographics
depression
Diabetes
Diabetes Mellitus - epidemiology
Epidemiology
Female
Gender Differences
Humans
hyperglycaemia
Hyperglycemia
Hypertension
Incidence
Intellectual disabilities
Intellectual Disability
Intellectual Disability - epidemiology
Male
Mental depression
Meta Analysis
Prevalence
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Summary:Background This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population controls. Methods Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta‐analysis and an odds ratio analysis were conducted to compare rates with controls. Results The trim‐ and fill‐adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities (N studies = 33) was 8.5% (95% CI = 7.2%–10.0%). The trim‐ and fill‐adjusted odds for diabetes was 2.46 times higher (95% CI = 1.89–3.21) (n = 42,684) versus controls (n = 4,177,550). Older age (R2 = .83, p 
ISSN:1360-2322
1468-3148
DOI:10.1111/jar.12949