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Prevalence of diabetes in people with intellectual disabilities and age‐ and gender‐matched controls: A meta‐analysis
Background This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population...
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| Published in: | Journal of applied research in intellectual disabilities 2022-03, Vol.35 (2), p.301-311 |
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| Main Authors: | , , , , , , |
| Format: | Article |
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| cited_by | cdi_FETCH-LOGICAL-c4109-9994c93e13d4dde19b655d171942f485cd66612b463c0eac91180991aa3c8a863 |
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| cites | cdi_FETCH-LOGICAL-c4109-9994c93e13d4dde19b655d171942f485cd66612b463c0eac91180991aa3c8a863 |
| container_end_page | 311 |
| container_issue | 2 |
| container_start_page | 301 |
| container_title | Journal of applied research in intellectual disabilities |
| container_volume | 35 |
| creator | Vancampfort, Davy Schuch, Felipe Van Damme, Tine Firth, Joseph Suetani, Shuichi Stubbs, Brendon Van Biesen, Debbie |
| description | Background
This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population controls.
Methods
Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta‐analysis and an odds ratio analysis were conducted to compare rates with controls.
Results
The trim‐ and fill‐adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities (N studies = 33) was 8.5% (95% CI = 7.2%–10.0%). The trim‐ and fill‐adjusted odds for diabetes was 2.46 times higher (95% CI = 1.89–3.21) (n = 42,684) versus controls (n = 4,177,550).
Older age (R2 = .83, p |
| doi_str_mv | 10.1111/jar.12949 |
| format | article |
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This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population controls.
Methods
Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta‐analysis and an odds ratio analysis were conducted to compare rates with controls.
Results
The trim‐ and fill‐adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities (N studies = 33) was 8.5% (95% CI = 7.2%–10.0%). The trim‐ and fill‐adjusted odds for diabetes was 2.46 times higher (95% CI = 1.89–3.21) (n = 42,684) versus controls (n = 4,177,550).
Older age (R2 = .83, p < .001), smoking (R2 = .30, p = .009) and co‐morbid depression (R2 = .18, p = .04), anxiety (R2 = .97, p < .001), and hypertension (R2 = 0.29, p < .001) were associated with higher diabetes prevalence rates.
Conclusions
Our findings demonstrate that people with intellectual disabilities are at an increased risk of diabetes, and therefore routine screening and multidisciplinary management of diabetes is needed.</description><identifier>ISSN: 1360-2322</identifier><identifier>EISSN: 1468-3148</identifier><identifier>DOI: 10.1111/jar.12949</identifier><identifier>PMID: 34658096</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Age Differences ; Age groups ; Aged ; Anxiety ; Case-Control Studies ; Comorbidity ; Demographics ; depression ; Diabetes ; Diabetes Mellitus - epidemiology ; Epidemiology ; Female ; Gender Differences ; Humans ; hyperglycaemia ; Hyperglycemia ; Hypertension ; Incidence ; Intellectual disabilities ; Intellectual Disability ; Intellectual Disability - epidemiology ; Male ; Mental depression ; Meta Analysis ; Prevalence</subject><ispartof>Journal of applied research in intellectual disabilities, 2022-03, Vol.35 (2), p.301-311</ispartof><rights>2021 John Wiley & Sons Ltd.</rights><rights>2022 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4109-9994c93e13d4dde19b655d171942f485cd66612b463c0eac91180991aa3c8a863</citedby><cites>FETCH-LOGICAL-c4109-9994c93e13d4dde19b655d171942f485cd66612b463c0eac91180991aa3c8a863</cites><orcidid>0000-0002-2754-4679 ; 0000-0002-4592-8625</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://eric.ed.gov/ERICWebPortal/detail?accno=EJ1326773$$DView record in ERIC$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34658096$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vancampfort, Davy</creatorcontrib><creatorcontrib>Schuch, Felipe</creatorcontrib><creatorcontrib>Van Damme, Tine</creatorcontrib><creatorcontrib>Firth, Joseph</creatorcontrib><creatorcontrib>Suetani, Shuichi</creatorcontrib><creatorcontrib>Stubbs, Brendon</creatorcontrib><creatorcontrib>Van Biesen, Debbie</creatorcontrib><title>Prevalence of diabetes in people with intellectual disabilities and age‐ and gender‐matched controls: A meta‐analysis</title><title>Journal of applied research in intellectual disabilities</title><addtitle>J Appl Res Intellect Disabil</addtitle><description>Background
This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population controls.
Methods
Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta‐analysis and an odds ratio analysis were conducted to compare rates with controls.
Results
The trim‐ and fill‐adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities (N studies = 33) was 8.5% (95% CI = 7.2%–10.0%). The trim‐ and fill‐adjusted odds for diabetes was 2.46 times higher (95% CI = 1.89–3.21) (n = 42,684) versus controls (n = 4,177,550).
Older age (R2 = .83, p < .001), smoking (R2 = .30, p = .009) and co‐morbid depression (R2 = .18, p = .04), anxiety (R2 = .97, p < .001), and hypertension (R2 = 0.29, p < .001) were associated with higher diabetes prevalence rates.
Conclusions
Our findings demonstrate that people with intellectual disabilities are at an increased risk of diabetes, and therefore routine screening and multidisciplinary management of diabetes is needed.</description><subject>Age Differences</subject><subject>Age groups</subject><subject>Aged</subject><subject>Anxiety</subject><subject>Case-Control Studies</subject><subject>Comorbidity</subject><subject>Demographics</subject><subject>depression</subject><subject>Diabetes</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Gender Differences</subject><subject>Humans</subject><subject>hyperglycaemia</subject><subject>Hyperglycemia</subject><subject>Hypertension</subject><subject>Incidence</subject><subject>Intellectual disabilities</subject><subject>Intellectual Disability</subject><subject>Intellectual Disability - epidemiology</subject><subject>Male</subject><subject>Mental depression</subject><subject>Meta Analysis</subject><subject>Prevalence</subject><issn>1360-2322</issn><issn>1468-3148</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>7SW</sourceid><recordid>eNp1kc1u1DAQxy0Eoh9w4AFAlrjAIa3Hdrxxb6uq0FaVQAjOkWPPtl45yWI7VCsufQSesU9Styk9IDGXmdH_p_nQn5A3wA6gxOHaxAPgWupnZBekaioBsnleaqFYxQXnO2QvpTVjrIF68ZLsCKnqhmm1S35_jfjLBBws0nFFnTcdZkzUD3SD4yYgvfb5qrQZQ0CbJxMKlEzng8--gGZw1Fzi7c2fh_ISB4exdL3J9godteOQ4xjSEV3SHrMpkhlM2CafXpEXKxMSvn7M--THp5Pvx6fVxZfPZ8fLi8pKYLrSWkurBYJw0jkE3am6drAALflKNrV1SingnVTCMjRWA5TfNBgjbGMaJfbJh3nuJo4_J0y57X2y5R8z4DillteNEBwY3KPv_0HX4xTLvYVSXIOqQdSF-jhTNo4pRVy1m-h7E7ctsPbekbY40j44Uth3jxOnrkf3RP61oABvZwCjt0_yyTkIrhYLUfTDWb_2Abf_39SeL7_NK-8ANsahCg</recordid><startdate>202203</startdate><enddate>202203</enddate><creator>Vancampfort, Davy</creator><creator>Schuch, Felipe</creator><creator>Van Damme, Tine</creator><creator>Firth, Joseph</creator><creator>Suetani, Shuichi</creator><creator>Stubbs, Brendon</creator><creator>Van Biesen, Debbie</creator><general>Blackwell Publishing Ltd</general><general>Wiley</general><general>Wiley Subscription Services, Inc</general><scope>7SW</scope><scope>BJH</scope><scope>BNH</scope><scope>BNI</scope><scope>BNJ</scope><scope>BNO</scope><scope>ERI</scope><scope>PET</scope><scope>REK</scope><scope>WWN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2754-4679</orcidid><orcidid>https://orcid.org/0000-0002-4592-8625</orcidid></search><sort><creationdate>202203</creationdate><title>Prevalence of diabetes in people with intellectual disabilities and age‐ and gender‐matched controls: A meta‐analysis</title><author>Vancampfort, Davy ; Schuch, Felipe ; Van Damme, Tine ; Firth, Joseph ; Suetani, Shuichi ; Stubbs, Brendon ; Van Biesen, Debbie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4109-9994c93e13d4dde19b655d171942f485cd66612b463c0eac91180991aa3c8a863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Age Differences</topic><topic>Age groups</topic><topic>Aged</topic><topic>Anxiety</topic><topic>Case-Control Studies</topic><topic>Comorbidity</topic><topic>Demographics</topic><topic>depression</topic><topic>Diabetes</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Gender Differences</topic><topic>Humans</topic><topic>hyperglycaemia</topic><topic>Hyperglycemia</topic><topic>Hypertension</topic><topic>Incidence</topic><topic>Intellectual disabilities</topic><topic>Intellectual Disability</topic><topic>Intellectual Disability - epidemiology</topic><topic>Male</topic><topic>Mental depression</topic><topic>Meta Analysis</topic><topic>Prevalence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vancampfort, Davy</creatorcontrib><creatorcontrib>Schuch, Felipe</creatorcontrib><creatorcontrib>Van Damme, Tine</creatorcontrib><creatorcontrib>Firth, Joseph</creatorcontrib><creatorcontrib>Suetani, Shuichi</creatorcontrib><creatorcontrib>Stubbs, Brendon</creatorcontrib><creatorcontrib>Van Biesen, Debbie</creatorcontrib><collection>ERIC</collection><collection>ERIC (Ovid)</collection><collection>ERIC</collection><collection>ERIC</collection><collection>ERIC (Legacy Platform)</collection><collection>ERIC( SilverPlatter )</collection><collection>ERIC</collection><collection>ERIC PlusText (Legacy Platform)</collection><collection>Education Resources Information Center (ERIC)</collection><collection>ERIC</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of applied research in intellectual disabilities</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vancampfort, Davy</au><au>Schuch, Felipe</au><au>Van Damme, Tine</au><au>Firth, Joseph</au><au>Suetani, Shuichi</au><au>Stubbs, Brendon</au><au>Van Biesen, Debbie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><ericid>EJ1326773</ericid><atitle>Prevalence of diabetes in people with intellectual disabilities and age‐ and gender‐matched controls: A meta‐analysis</atitle><jtitle>Journal of applied research in intellectual disabilities</jtitle><addtitle>J Appl Res Intellect Disabil</addtitle><date>2022-03</date><risdate>2022</risdate><volume>35</volume><issue>2</issue><spage>301</spage><epage>311</epage><pages>301-311</pages><issn>1360-2322</issn><eissn>1468-3148</eissn><abstract>Background
This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population controls.
Methods
Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta‐analysis and an odds ratio analysis were conducted to compare rates with controls.
Results
The trim‐ and fill‐adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities (N studies = 33) was 8.5% (95% CI = 7.2%–10.0%). The trim‐ and fill‐adjusted odds for diabetes was 2.46 times higher (95% CI = 1.89–3.21) (n = 42,684) versus controls (n = 4,177,550).
Older age (R2 = .83, p < .001), smoking (R2 = .30, p = .009) and co‐morbid depression (R2 = .18, p = .04), anxiety (R2 = .97, p < .001), and hypertension (R2 = 0.29, p < .001) were associated with higher diabetes prevalence rates.
Conclusions
Our findings demonstrate that people with intellectual disabilities are at an increased risk of diabetes, and therefore routine screening and multidisciplinary management of diabetes is needed.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>34658096</pmid><doi>10.1111/jar.12949</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-2754-4679</orcidid><orcidid>https://orcid.org/0000-0002-4592-8625</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1360-2322 |
| ispartof | Journal of applied research in intellectual disabilities, 2022-03, Vol.35 (2), p.301-311 |
| issn | 1360-2322 1468-3148 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2583321016 |
| source | Wiley-Blackwell Read & Publish Collection; ERIC |
| subjects | Age Differences Age groups Aged Anxiety Case-Control Studies Comorbidity Demographics depression Diabetes Diabetes Mellitus - epidemiology Epidemiology Female Gender Differences Humans hyperglycaemia Hyperglycemia Hypertension Incidence Intellectual disabilities Intellectual Disability Intellectual Disability - epidemiology Male Mental depression Meta Analysis Prevalence |
| title | Prevalence of diabetes in people with intellectual disabilities and age‐ and gender‐matched controls: A meta‐analysis |
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