Impact of nocturnal hypoxemia on the recurrence of atrial tachyarrhythmia after catheter ablation of atrial fibrillation

Factors causing atrial tachyarrhythmia recurrence after catheter ablation (CA) of atrial fibrillation (AF) remain undetermined. This study aimed to investigate the effect of nocturnal hypoxemia on the recurrence of atrial tachyarrhythmia after CA of AF. Among 594 patients with AF who underwent an am...

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Bibliographic Details
Published in:Heart and vessels 2022-05, Vol.37 (5), p.794-801
Main Authors: Suzuki, Keisuke, Miyamoto, Koji, Wakamiya, Akinori, Ueda, Nobuhiko, Nakajima, Kenzaburo, Kamakura, Tsukasa, Wada, Mitsuru, Yamagata, Kenichiro, Ishibashi, Kohei, Inoue, Yuko, Noda, Takashi, Nagase, Satoshi, Aiba, Takeshi, Yambe, Tomoyuki, Kusano, Kengo
Format: Article
Language:English
Subjects:
Ablation
Apnea
Atrial Fibrillation - complications
Atrial Fibrillation - diagnosis
Atrial Fibrillation - surgery
Biomedical Engineering and Bioengineering
Cardiac arrhythmia
Cardiac Surgery
Cardiology
Catheter Ablation - adverse effects
Catheters
Confidence intervals
Continuous positive airway pressure
Fibrillation
Heart Atria
Humans
Hypoxemia
Hypoxia
Hypoxia - complications
Independent variables
Mathematical analysis
Medical instruments
Medicine
Medicine & Public Health
Multivariate analysis
Original Article
Patients
Radiofrequency ablation
Recurrence
Regression analysis
Risk Factors
Sleep
Sleep disorders
Statistical analysis
Tachyarrhythmia
Tachycardia - complications
Tachycardia - surgery
Treatment Outcome
Vascular Surgery
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Summary:Factors causing atrial tachyarrhythmia recurrence after catheter ablation (CA) of atrial fibrillation (AF) remain undetermined. This study aimed to investigate the effect of nocturnal hypoxemia on the recurrence of atrial tachyarrhythmia after CA of AF. Among 594 patients with AF who underwent an ambulatory sleep study at the National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (2014–2019), 365 underwent CA of AF; 290 patients who underwent CA were followed up for > 3 months. Multivariate Cox regression analysis was used to calculate hazard ratios (HRs) using clinical variables, to identify the independent predictors of atrial tachyarrhythmia recurrence after the final CA. Atrial tachyarrhythmia recurred in 45 of 290 (15.5%) patients during the median follow-up period of 479 days (interquartile range 225–1002). On the performing multivariate analysis of the data of patients who did not receive continuous positive airway pressure (CPAP), severe nocturnal hypoxemia [defined as the percentage of sleep time spent with SaO 2 of 
ISSN:0910-8327
1615-2573
DOI:10.1007/s00380-021-01969-x