Feeding and Growth Outcomes in Infants with Type C Esophageal Atresia Who Undergo Early Primary Repair

To describe growth and feeding outcomes in patients with type C esophageal atresia who underwent early primary repair and to identify predictors for poor growth. This single-center, retrospective, cohort study included all patients with type C esophageal atresia who underwent early primary repair fr...

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Bibliographic Details
Published in:The Journal of pediatrics 2022-02, Vol.241, p.77-82.e1
Main Authors: Harrington, Amanda W., Riebold, Jane, Hernandez, Kayla, Staffa, Steven J., Meisner, Jay W., Zurakowski, David, Jennings, Russell, Hamilton, Thomas, Zendejas, Benjamin
Format: Article
Language:English
Subjects:
Child Development
Child, Preschool
Cohort Studies
esophageal atresia
Esophageal Atresia - surgery
Female
growth
Humans
Infant
Infant, Newborn
Male
Nutritional Status
Retrospective Studies
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Summary:To describe growth and feeding outcomes in patients with type C esophageal atresia who underwent early primary repair and to identify predictors for poor growth. This single-center, retrospective, cohort study included all patients with type C esophageal atresia who underwent early primary repair from 2013 to 2019. Weight-for-age z score (WAZ) was calculated at birth, and every 6 months until 3 years postoperatively. Longitudinal median regression was used to evaluate WAZ over time. A multivariable logistic regression model explored predictors of growth outcomes. Of 46 infants who met the inclusion criteria, 72% were term. The median age at repair was 1.5 days of life (IQR, 1-2 days of life) and the hospital length of stay was 20 days (IQR-14, 30 days). Two patients had esophageal leak (4.3%). The median WAZ at birth was below average (−0.72; IQR, −1.37 to −0.40), but improved to reach average by 3 years (−0.025; IQR, −0.85 to 0.97, P 
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2021.10.012