Neonatal sepsis in dogs: Incidence, clinical aspects and mortality

• Published in: Theriogenology 2022-01, Vol.177, p.103-115
• Main Authors: Nobre Pacifico Pereira, Keylla Helena, Fuchs, Kárita da Mata, Hibaru, Viviane Yukari, Cruz dos Santos Correia, Luiz Eduardo, Ferreira, João Carlos Pinheiro, Ferreira de Souza, Fabiana, Machado, Luiz Henrique de Araújo, Chiacchio, Simone Biagio, Gomes Lourenço, Maria Lucia
• Format: Article
• Language: English
• Subjects: Bacterial infection; Neonate; Newborn dog; Puppy; Septic shock
• ISSN: 0093-691X; 1879-3231
• DOI: 10.1016/j.theriogenology.2021.10.015

The neonatal period in dogs remains associated with high mortality rates. Sepsis is the main cause of neonatal losses during the first three weeks of life. Additionally, failure in the clinical assessment and early diagnosis of sick newborns is still common, leading to inadequate care, which contributes to a high mortality rate. Thus, the objective of this study was to describe the incidence of sepsis in canine newborns, the clinical aspects involved, the main isolated bacterial agents and mortality rates to facilitate clinicians’ early recognition of this condition. Of the 152 litters and 762 neonates evaluated, 14.8% (113/762) had sepsis or septic shock, and the mortality rate among affected puppies was 25.6% (29/113). Among the puppies with sepsis that died, early mortality (0–2 days of age) occurred in 69% (20/29) of affected neonates, and late mortality (3–30 days of age) occurred in 31% (9/29) of affected neonates. Significant differences (p